Structure and function of mammalian sodium-dependent multivitamin transporter

Puttur D Prasad, Vadivel Ganapathy

Research output: Contribution to journalReview article

38 Citations (Scopus)

Abstract

This review focuses on the advances made in recent years in the understanding of the multivitamin transporter, a unique and important transporter that transports not one but three different unrelated water- soluble vitamins namely, pantothenate, biotin and lipoate. The transport process mediated by the transporter is active and is energized by the transmembrane sodium ion gradient as well as the membrane potential. The transporter belongs to the sodium-coupled glucose transporter family. The ubiquitous expression of this transporter in mammalian tissues and the fact that it is highly conserved across the species indicate the nutritional relevance and importance of this transporter. (C) 2000 Lippincott Williams and Wilkins.

Original languageEnglish (US)
Pages (from-to)263-266
Number of pages4
JournalCurrent Opinion in Clinical Nutrition and Metabolic Care
Volume3
Issue number4
DOIs
StatePublished - Jul 1 2000

Fingerprint

Sodium-Glucose Transport Proteins
Biotin
Vitamins
Membrane Potentials
transporters
Sodium
sodium
Ions
Water
water-soluble vitamins
glucose transporters
biotin
membrane potential
ions

ASJC Scopus subject areas

  • Medicine (miscellaneous)
  • Nutrition and Dietetics

Cite this

Structure and function of mammalian sodium-dependent multivitamin transporter. / Prasad, Puttur D; Ganapathy, Vadivel.

In: Current Opinion in Clinical Nutrition and Metabolic Care, Vol. 3, No. 4, 01.07.2000, p. 263-266.

Research output: Contribution to journalReview article

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