Study of dose enhancement effects in the vicinity of high Z atoms with Geant4 Monte Carlo simulation

Ke Huang, Kaiguo Yan, Yan Yu

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Dose enhancements in the vicinity of different high Z (HZ) materials in radiation therapy (RT) are studied by several groups. In this work, extensive and systematic Monte Carlo (MC) studies were performed with Geant4 toolkit focusing on factors that influence the dose enhancements, including the atomic number of HZ materials, the concentration of the HZ material, and the X-ray energies. Gold (Au), Platinum (Pt), Gadolinium (Gd), and Iodine (I) are used in the study. A new method has been implemented to determine the individual contributions from pair production, Compton scattering and the photoelectric effect to the total dose. The dose enhancement ratios (DERs) and their contributions to the overall dose deposition are calculated for these processes. It is also shown in the study that with fixed X-ray energy and molar concentration, the DERs for these HZ materials are approximately linear proportional to their Z number. The DER increases linearly with HZ concentration; however, the slope of the increase depends on the X-ray energies. Analysis of the DERs from different processes reveals an interesting phenomenon: although the contribution from the photoelectric effect to the overall dose enhancement for X-rays in the MeV range is low, being normally less than 3%, the DER for the photoelectric effect from MeV X-rays are higher than that from X-rays in keV range.

Original languageEnglish (US)
Title of host publicationProceedings - 2010 3rd International Conference on Biomedical Engineering and Informatics, BMEI 2010
Pages1260-1264
Number of pages5
Volume3
DOIs
StatePublished - Dec 1 2010
Event3rd International Conference on BioMedical Engineering and Informatics, BMEI 2010 - Yantai, China
Duration: Oct 16 2010Oct 18 2010

Other

Other3rd International Conference on BioMedical Engineering and Informatics, BMEI 2010
CountryChina
CityYantai
Period10/16/1010/18/10

Keywords

  • Contribution from processes
  • Dose enhancement
  • Gold
  • High Z
  • Radiation therapy
  • X-rays

ASJC Scopus subject areas

  • Biomedical Engineering
  • Health Informatics
  • Health Information Management

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  • Cite this

    Huang, K., Yan, K., & Yu, Y. (2010). Study of dose enhancement effects in the vicinity of high Z atoms with Geant4 Monte Carlo simulation. In Proceedings - 2010 3rd International Conference on Biomedical Engineering and Informatics, BMEI 2010 (Vol. 3, pp. 1260-1264). [5639270] https://doi.org/10.1109/BMEI.2010.5639270