SU‐E‐T‐108: 3D Measurement of Neutron Dose from a Novel Neutron Imaging Technique

A. Kapadia, A. Crowell, B. Fallin, C. Howell, G. Agasthya, M. Lakshmanan, Joseph R Newton, T. Juang, M. Oldham

Research output: Contribution to journalArticle

Abstract

Purpose: We have been developing a fast‐neutron spectroscopic technique to quantitatively image the distribution of elements in the body using quasi‐monochromatic neutron beams. Previously, we demonstrated the ability of the technique to quantify specific elements in the liver and breast while limiting radiation dose to clinically acceptable levels. Here we present the results of a physical dose measurement performed through neutron irradiation of 3D PRESAGE dosimetry phantoms. Methods: Two PRESAGE optical‐CT dosimeters were placed inside a physical phantom of the human torso and irradiated with 8 MeV neutrons produced via the 2H(d,n) reaction using a tandem Van‐de‐Graaff accelerator. The dosimeters, measuring 10 cm and 4 cm in diameter, were located in regions corresponding to the liver (10 cm), and the kidney (4 cm). Irradiation was performed with the neutron beam incident directly on the larger dosimeter. Cumulative neutron fluence incident upon each dosimeter was determined using an aluminum‐foil activation technique. Following irradiation, the change in optical density in both dosimeters was measured to determine the relative irradiation and dose distribution in each volume. Results: Both PRESAGE dosimeters exhibited detectable changes in optical density corresponding to the dose deposited in the volume. The two dosimeters registered doses of 8.5 Gy (direct incidence, 4.5 hour irradiation) and 0.25 Gy (off‐axis, 20 hour irradiation), respectively. The larger dosimeter showed highest intensity at the entry point of the beam with exponential drop‐off along the beam direction. The smaller dosimeter registered a more uniform change in intensity, consistent with the higher incidence of scattered neutrons at this location. Conclusion: The results demonstrate the utility of PRESAGE dosimeters in measuring dose from neutron irradiation and highlight the difference in relative doses between primary and proximal organs when exposed to neutron beams. This work was supported by the United States Department of Energy, Office of Nuclear Physics under Grant No. DE‐FG02‐97ER41033, the National Cancer Institute under grant R01CA100835, and by the Department of Defense under award W81XWH‐09‐1‐0066.

Original languageEnglish (US)
Pages (from-to)3727
Number of pages1
JournalMedical Physics
Volume39
Issue number6
DOIs
StatePublished - 2012
Externally publishedYes

Fingerprint

Neutrons
Nuclear Physics
Radiation Dosimeters
Torso
National Cancer Institute (U.S.)
Organized Financing
Liver
Incidence
Breast
Radiation
Kidney

ASJC Scopus subject areas

  • Biophysics
  • Radiology Nuclear Medicine and imaging

Cite this

Kapadia, A., Crowell, A., Fallin, B., Howell, C., Agasthya, G., Lakshmanan, M., ... Oldham, M. (2012). SU‐E‐T‐108: 3D Measurement of Neutron Dose from a Novel Neutron Imaging Technique. Medical Physics, 39(6), 3727. https://doi.org/10.1118/1.4735166

SU‐E‐T‐108 : 3D Measurement of Neutron Dose from a Novel Neutron Imaging Technique. / Kapadia, A.; Crowell, A.; Fallin, B.; Howell, C.; Agasthya, G.; Lakshmanan, M.; Newton, Joseph R; Juang, T.; Oldham, M.

In: Medical Physics, Vol. 39, No. 6, 2012, p. 3727.

Research output: Contribution to journalArticle

Kapadia, A, Crowell, A, Fallin, B, Howell, C, Agasthya, G, Lakshmanan, M, Newton, JR, Juang, T & Oldham, M 2012, 'SU‐E‐T‐108: 3D Measurement of Neutron Dose from a Novel Neutron Imaging Technique', Medical Physics, vol. 39, no. 6, pp. 3727. https://doi.org/10.1118/1.4735166
Kapadia A, Crowell A, Fallin B, Howell C, Agasthya G, Lakshmanan M et al. SU‐E‐T‐108: 3D Measurement of Neutron Dose from a Novel Neutron Imaging Technique. Medical Physics. 2012;39(6):3727. https://doi.org/10.1118/1.4735166
Kapadia, A. ; Crowell, A. ; Fallin, B. ; Howell, C. ; Agasthya, G. ; Lakshmanan, M. ; Newton, Joseph R ; Juang, T. ; Oldham, M. / SU‐E‐T‐108 : 3D Measurement of Neutron Dose from a Novel Neutron Imaging Technique. In: Medical Physics. 2012 ; Vol. 39, No. 6. pp. 3727.
@article{86b8e9b03cae434fb54a679a4ad2fd53,
title = "SU‐E‐T‐108: 3D Measurement of Neutron Dose from a Novel Neutron Imaging Technique",
abstract = "Purpose: We have been developing a fast‐neutron spectroscopic technique to quantitatively image the distribution of elements in the body using quasi‐monochromatic neutron beams. Previously, we demonstrated the ability of the technique to quantify specific elements in the liver and breast while limiting radiation dose to clinically acceptable levels. Here we present the results of a physical dose measurement performed through neutron irradiation of 3D PRESAGE dosimetry phantoms. Methods: Two PRESAGE optical‐CT dosimeters were placed inside a physical phantom of the human torso and irradiated with 8 MeV neutrons produced via the 2H(d,n) reaction using a tandem Van‐de‐Graaff accelerator. The dosimeters, measuring 10 cm and 4 cm in diameter, were located in regions corresponding to the liver (10 cm), and the kidney (4 cm). Irradiation was performed with the neutron beam incident directly on the larger dosimeter. Cumulative neutron fluence incident upon each dosimeter was determined using an aluminum‐foil activation technique. Following irradiation, the change in optical density in both dosimeters was measured to determine the relative irradiation and dose distribution in each volume. Results: Both PRESAGE dosimeters exhibited detectable changes in optical density corresponding to the dose deposited in the volume. The two dosimeters registered doses of 8.5 Gy (direct incidence, 4.5 hour irradiation) and 0.25 Gy (off‐axis, 20 hour irradiation), respectively. The larger dosimeter showed highest intensity at the entry point of the beam with exponential drop‐off along the beam direction. The smaller dosimeter registered a more uniform change in intensity, consistent with the higher incidence of scattered neutrons at this location. Conclusion: The results demonstrate the utility of PRESAGE dosimeters in measuring dose from neutron irradiation and highlight the difference in relative doses between primary and proximal organs when exposed to neutron beams. This work was supported by the United States Department of Energy, Office of Nuclear Physics under Grant No. DE‐FG02‐97ER41033, the National Cancer Institute under grant R01CA100835, and by the Department of Defense under award W81XWH‐09‐1‐0066.",
author = "A. Kapadia and A. Crowell and B. Fallin and C. Howell and G. Agasthya and M. Lakshmanan and Newton, {Joseph R} and T. Juang and M. Oldham",
year = "2012",
doi = "10.1118/1.4735166",
language = "English (US)",
volume = "39",
pages = "3727",
journal = "Medical Physics",
issn = "0094-2405",
publisher = "AAPM - American Association of Physicists in Medicine",
number = "6",

}

TY - JOUR

T1 - SU‐E‐T‐108

T2 - 3D Measurement of Neutron Dose from a Novel Neutron Imaging Technique

AU - Kapadia, A.

AU - Crowell, A.

AU - Fallin, B.

AU - Howell, C.

AU - Agasthya, G.

AU - Lakshmanan, M.

AU - Newton, Joseph R

AU - Juang, T.

AU - Oldham, M.

PY - 2012

Y1 - 2012

N2 - Purpose: We have been developing a fast‐neutron spectroscopic technique to quantitatively image the distribution of elements in the body using quasi‐monochromatic neutron beams. Previously, we demonstrated the ability of the technique to quantify specific elements in the liver and breast while limiting radiation dose to clinically acceptable levels. Here we present the results of a physical dose measurement performed through neutron irradiation of 3D PRESAGE dosimetry phantoms. Methods: Two PRESAGE optical‐CT dosimeters were placed inside a physical phantom of the human torso and irradiated with 8 MeV neutrons produced via the 2H(d,n) reaction using a tandem Van‐de‐Graaff accelerator. The dosimeters, measuring 10 cm and 4 cm in diameter, were located in regions corresponding to the liver (10 cm), and the kidney (4 cm). Irradiation was performed with the neutron beam incident directly on the larger dosimeter. Cumulative neutron fluence incident upon each dosimeter was determined using an aluminum‐foil activation technique. Following irradiation, the change in optical density in both dosimeters was measured to determine the relative irradiation and dose distribution in each volume. Results: Both PRESAGE dosimeters exhibited detectable changes in optical density corresponding to the dose deposited in the volume. The two dosimeters registered doses of 8.5 Gy (direct incidence, 4.5 hour irradiation) and 0.25 Gy (off‐axis, 20 hour irradiation), respectively. The larger dosimeter showed highest intensity at the entry point of the beam with exponential drop‐off along the beam direction. The smaller dosimeter registered a more uniform change in intensity, consistent with the higher incidence of scattered neutrons at this location. Conclusion: The results demonstrate the utility of PRESAGE dosimeters in measuring dose from neutron irradiation and highlight the difference in relative doses between primary and proximal organs when exposed to neutron beams. This work was supported by the United States Department of Energy, Office of Nuclear Physics under Grant No. DE‐FG02‐97ER41033, the National Cancer Institute under grant R01CA100835, and by the Department of Defense under award W81XWH‐09‐1‐0066.

AB - Purpose: We have been developing a fast‐neutron spectroscopic technique to quantitatively image the distribution of elements in the body using quasi‐monochromatic neutron beams. Previously, we demonstrated the ability of the technique to quantify specific elements in the liver and breast while limiting radiation dose to clinically acceptable levels. Here we present the results of a physical dose measurement performed through neutron irradiation of 3D PRESAGE dosimetry phantoms. Methods: Two PRESAGE optical‐CT dosimeters were placed inside a physical phantom of the human torso and irradiated with 8 MeV neutrons produced via the 2H(d,n) reaction using a tandem Van‐de‐Graaff accelerator. The dosimeters, measuring 10 cm and 4 cm in diameter, were located in regions corresponding to the liver (10 cm), and the kidney (4 cm). Irradiation was performed with the neutron beam incident directly on the larger dosimeter. Cumulative neutron fluence incident upon each dosimeter was determined using an aluminum‐foil activation technique. Following irradiation, the change in optical density in both dosimeters was measured to determine the relative irradiation and dose distribution in each volume. Results: Both PRESAGE dosimeters exhibited detectable changes in optical density corresponding to the dose deposited in the volume. The two dosimeters registered doses of 8.5 Gy (direct incidence, 4.5 hour irradiation) and 0.25 Gy (off‐axis, 20 hour irradiation), respectively. The larger dosimeter showed highest intensity at the entry point of the beam with exponential drop‐off along the beam direction. The smaller dosimeter registered a more uniform change in intensity, consistent with the higher incidence of scattered neutrons at this location. Conclusion: The results demonstrate the utility of PRESAGE dosimeters in measuring dose from neutron irradiation and highlight the difference in relative doses between primary and proximal organs when exposed to neutron beams. This work was supported by the United States Department of Energy, Office of Nuclear Physics under Grant No. DE‐FG02‐97ER41033, the National Cancer Institute under grant R01CA100835, and by the Department of Defense under award W81XWH‐09‐1‐0066.

UR - http://www.scopus.com/inward/record.url?scp=85024801256&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85024801256&partnerID=8YFLogxK

U2 - 10.1118/1.4735166

DO - 10.1118/1.4735166

M3 - Article

AN - SCOPUS:85024801256

VL - 39

SP - 3727

JO - Medical Physics

JF - Medical Physics

SN - 0094-2405

IS - 6

ER -