Abstract
Radioactive strontium chloride ( 89Sr) was administered for pain relief in 6 patients with bone metastases (4 prostate cancer and 2 breast cancer patients). Out of 6 patients, 2 showed apparent relief of bone pain and improvement of QOL, and 3 showed slight relief of the pain with or without improvement of QOL; that is, 83% was effective. Side effects were seen in 2 patients; transient deterioration of bone pain in one patient and bone marrow suppression in the other patient. The patient who showed bone marrow suppression had rather more lesions of bone metastasis (diffuse metastasis) and least urinary excretion of the radioactivity. Urinary excretion for 2 days varied 5 to 40% of the administered dose and was less in the patients with more metastatic lesions.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 1243-1248 |
| Number of pages | 6 |
| Journal | Kakuigaku |
| Volume | 33 |
| Issue number | 11 |
| State | Published - Dec 1 1996 |
| Externally published | Yes |
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Keywords
- Bone metastasis
- Pain relief
- Radionuclide therapy
- Sr
ASJC Scopus subject areas
- Radiology Nuclear Medicine and imaging
Cite this
89Sr therapy for pain relief in patients with bone metastases. / Koizumi, Kiyoshi; Arbab, Ali Syed; Toyama, Keiji; Shirasu, Masayo; Osawa, Sachiko; Araki, Takuji; Yamaguchi, Motoshi; Onishi, Hiroshi; Araki, Tsutomu; Arai, Takao; Komatsu, Hideki; Ueno, Akira; Nokata, Hisashi.
In: Kakuigaku, Vol. 33, No. 11, 01.12.1996, p. 1243-1248.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - 89Sr therapy for pain relief in patients with bone metastases
AU - Koizumi, Kiyoshi
AU - Arbab, Ali Syed
AU - Toyama, Keiji
AU - Shirasu, Masayo
AU - Osawa, Sachiko
AU - Araki, Takuji
AU - Yamaguchi, Motoshi
AU - Onishi, Hiroshi
AU - Araki, Tsutomu
AU - Arai, Takao
AU - Komatsu, Hideki
AU - Ueno, Akira
AU - Nokata, Hisashi
PY - 1996/12/1
Y1 - 1996/12/1
N2 - Radioactive strontium chloride ( 89Sr) was administered for pain relief in 6 patients with bone metastases (4 prostate cancer and 2 breast cancer patients). Out of 6 patients, 2 showed apparent relief of bone pain and improvement of QOL, and 3 showed slight relief of the pain with or without improvement of QOL; that is, 83% was effective. Side effects were seen in 2 patients; transient deterioration of bone pain in one patient and bone marrow suppression in the other patient. The patient who showed bone marrow suppression had rather more lesions of bone metastasis (diffuse metastasis) and least urinary excretion of the radioactivity. Urinary excretion for 2 days varied 5 to 40% of the administered dose and was less in the patients with more metastatic lesions.
AB - Radioactive strontium chloride ( 89Sr) was administered for pain relief in 6 patients with bone metastases (4 prostate cancer and 2 breast cancer patients). Out of 6 patients, 2 showed apparent relief of bone pain and improvement of QOL, and 3 showed slight relief of the pain with or without improvement of QOL; that is, 83% was effective. Side effects were seen in 2 patients; transient deterioration of bone pain in one patient and bone marrow suppression in the other patient. The patient who showed bone marrow suppression had rather more lesions of bone metastasis (diffuse metastasis) and least urinary excretion of the radioactivity. Urinary excretion for 2 days varied 5 to 40% of the administered dose and was less in the patients with more metastatic lesions.
KW - Bone metastasis
KW - Pain relief
KW - Radionuclide therapy
KW - Sr
UR - http://www.scopus.com/inward/record.url?scp=0030299789&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0030299789&partnerID=8YFLogxK
M3 - Article
VL - 33
SP - 1243
EP - 1248
JO - Kaku igaku. The Japanese journal of nuclear medicine
JF - Kaku igaku. The Japanese journal of nuclear medicine
SN - 0022-7854
IS - 11
ER -