Surface engineering of macrophages with nanoparticles to generate a cell-nanoparticle hybrid vehicle for hypoxia-targeted drug delivery

Engineering & Materials Science

• Targeted drug delivery 100%
• Macrophages 98%
• Hybrid vehicles 61%
• Nanoparticles 57%
• Amines 27%
• Tumors 23%
• Sodium 23%
• Cells 22%
• Dendrimers 20%
• Fluorescence imaging 18%
• Chemotherapy 17%
• Drug delivery 15%
• Reducing agents 15%
• Polyethylene glycols 15%
• Toxicity 13%
• Surface treatment 12%
• Oxygen 9%
• Radiation 9%

Medicine & Life Sciences

• Hybrid Cells 71%
• Nanoparticles 51%
• Hypoxia 46%
• Macrophages 40%
• Schiff Bases 34%
• Amines 24%
• Pharmaceutical Preparations 24%
• sodium cyanoborohydride 22%
• Poly(amidoamine) 17%
• Immobilized Cells 17%
• metaperiodate 16%
• Quantum Dots 16%
• Dendrimers 16%
• Neoplasms 15%
• Reducing Agents 14%
• Polyethylene Glycols 13%
• Optical Imaging 12%
• Fluorescein 12%
• Radiation 8%
• Poisons 8%
• Oxygen 8%
• Drug Therapy 6%
• Therapeutics 1%

Chemical Compounds

• Drug 30%
• Nanoparticle 29%
• Schiff Base 24%
• Surface 18%
• Sodium Atom 18%
• Secondary Amine 14%
• Dendrimer 14%
• Antineoplastic Agent 12%
• Quantum Dot 12%
• Reducing Agent 12%
• Surface Modification 12%
• Poly(ethylene Glycol) 11%
• Toxic 10%
• Fluorescence 8%
• Dioxygen 7%