Synthesis of deuterium-labelled 2,5-bis(4-amidinophenyl)furan, 2,5-bis[4-(methoxyamidino)phenyl]furan, and 2,7-diamidinocarbazole

Chad E. Stephens, Donald A. Patrick, Heidi Chen, Richard R. Tidwell, David W. Boykin

Research output: Contribution to journalArticle

15 Citations (Scopus)

Abstract

The syntheses of 2,5-bis(4-amidinophenyl)furan-d 8 (1-d 8 ) and 2,5-bis[4-(methoxyamidino)phenyl]furan-d 8 (2-d 8 ) from bromobenzene-d 5 in six steps, and of 2,7-diamidinocarbazole-d 6 (3-d 6 ) from biphenyl-d 10 in five steps, are described.

Original languageEnglish (US)
Pages (from-to)197-208
Number of pages12
JournalJournal of Labelled Compounds and Radiopharmaceuticals
Volume44
Issue number3
DOIs
StatePublished - Mar 19 2001
Externally publishedYes

Fingerprint

Deuterium
furamidine
furan
diphenyl
bromobenzene

Keywords

  • 2,5-bis(4-amidinophenyl)furan-d
  • 2,5-bis[4- (methoxyamidino)phenyl]furan-d
  • 2,7-diamidinocarbazole- d
  • Antimicrobial
  • Deuterium-labelled
  • Prodrug

ASJC Scopus subject areas

  • Analytical Chemistry
  • Biochemistry
  • Radiology Nuclear Medicine and imaging
  • Drug Discovery
  • Spectroscopy
  • Organic Chemistry

Cite this

Synthesis of deuterium-labelled 2,5-bis(4-amidinophenyl)furan, 2,5-bis[4-(methoxyamidino)phenyl]furan, and 2,7-diamidinocarbazole. / Stephens, Chad E.; Patrick, Donald A.; Chen, Heidi; Tidwell, Richard R.; Boykin, David W.

In: Journal of Labelled Compounds and Radiopharmaceuticals, Vol. 44, No. 3, 19.03.2001, p. 197-208.

Research output: Contribution to journalArticle

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