Synthesis of taurine-containing peptides, sulfonopeptides, and N - And O -conjugates

Peter Vertesaljai, Suvendu Biswas, Iryna Lebedyeva, Evan Broggi, Abdullah M. Asiri, Alan R. Katritzky

Research output: Contribution to journalArticle

7 Scopus citations

Abstract

Taurine-containing water-soluble peptidomimetics were designed and synthesized. N-terminal taurine acylations allowed synthesis of a number of taurine-containing peptides. N-protection of taurine with Cbz and SO 2-activation with benzotriazole followed by coupling with various amino esters, dipeptides and nucleophiles provided taurine N- and O-conjugates and sulfonopeptides.

Original languageEnglish (US)
Pages (from-to)2688-2693
Number of pages6
JournalJournal of Organic Chemistry
Volume79
Issue number6
DOIs
StatePublished - Mar 21 2014
Externally publishedYes

ASJC Scopus subject areas

  • Organic Chemistry

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  • Cite this

    Vertesaljai, P., Biswas, S., Lebedyeva, I., Broggi, E., Asiri, A. M., & Katritzky, A. R. (2014). Synthesis of taurine-containing peptides, sulfonopeptides, and N - And O -conjugates. Journal of Organic Chemistry, 79(6), 2688-2693. https://doi.org/10.1021/jo500181g