Abstract
Taurine-containing water-soluble peptidomimetics were designed and synthesized. N-terminal taurine acylations allowed synthesis of a number of taurine-containing peptides. N-protection of taurine with Cbz and SO 2-activation with benzotriazole followed by coupling with various amino esters, dipeptides and nucleophiles provided taurine N- and O-conjugates and sulfonopeptides.
Original language | English (US) |
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Pages (from-to) | 2688-2693 |
Number of pages | 6 |
Journal | Journal of Organic Chemistry |
Volume | 79 |
Issue number | 6 |
DOIs | |
State | Published - Mar 21 2014 |
Externally published | Yes |
ASJC Scopus subject areas
- Organic Chemistry