Abstract
Benzimidazoles are very useful building blocks for the development of molecules that are important in medicinal chemistry. 2- Substituted benzimidazole derivatives have found applications as diverse therapeutic agents, including antiulcers, antihypertensives, antivirals, antifungals, anticancers, and antihistaminics. Because of their importance, the methods for their synthesis have become a focus of Synthetic Organic Chemists. However, we failed to locate report in the literature that covers various efforts that have been made for the synthesis of 2-arylbenzimidazoles. Therefore, in the present review, we have tried to compile some of the important synthetic techniques and methodologies used for its synthesis during the last decade.
Original language | English (US) |
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Pages (from-to) | 1905-1919 |
Number of pages | 15 |
Journal | Current Organic Chemistry |
Volume | 16 |
Issue number | 16 |
DOIs | |
State | Published - 2012 |
Externally published | Yes |
Keywords
- 2-Arylbenzimidazoles
- Methodologies
- O-phenylenediamine
- Synthetic routes
ASJC Scopus subject areas
- Organic Chemistry