Syphilis and HIV infection: An update

Nicola M. Zetola, Jeffrey D. Klausner

Research output: Contribution to journalReview articlepeer-review

251 Scopus citations

Abstract

The striking increase in the prevalence of concordant human immunodeficiency virus (HIV) infection and syphilis observed by clinicians and public health officers over the past decade has renewed interest in the subject. Although the effect of HIV infection on the natural history of syphilis has been known for a long time, it was not until recently that several studies documented that syphilis may also impact the course of HIV infection. Despite an improved understanding of the interaction of these 2 conditions, many controversies still exist. In this article, we focus on the most recent literature describing the epidemiology, clinical manifestations, and treatment of syphilis in the context of HIV infection.

Original languageEnglish (US)
Pages (from-to)1222-1228
Number of pages7
JournalClinical Infectious Diseases
Volume44
Issue number9
DOIs
StatePublished - May 1 2007
Externally publishedYes

ASJC Scopus subject areas

  • Microbiology (medical)
  • Infectious Diseases

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