TY - JOUR
T1 - Syphilis in the United States
T2 - An update for clinicians with an emphasis on HIV coinfection
AU - Zetola, Nicola M.
AU - Engelman, Joseph
AU - Jensen, Trevor P.
AU - Klausner, Jeffrey D.
N1 - Funding Information:
This work was supported in part by the California HIV Research Program (CHRP) and the San Francisco Department of Public Health.
PY - 2007/9
Y1 - 2007/9
N2 - Diagnosis and treatment of syphilis are challenging because of its variable clinical presentation and course and the lack of definitive tests of cure after treatment. This review of the most recent literature on the epidemiology, clinical manifestations, current diagnosis, and treatment of syphilis is focused toward clinicians who treat patients with this disease. Syphilis coinfection with human immunodeficiency virus is emphasized because it is increasingly common in the United States and affects the initial presentation, disease course, diagnosis, and treatment of syphilis. Of particular consequence is the effect of human immunodeficiency virus on the clinical diagnosis, prevalence, and course of neurosyphilis, one of the most serious consequences of syphilis infection.
AB - Diagnosis and treatment of syphilis are challenging because of its variable clinical presentation and course and the lack of definitive tests of cure after treatment. This review of the most recent literature on the epidemiology, clinical manifestations, current diagnosis, and treatment of syphilis is focused toward clinicians who treat patients with this disease. Syphilis coinfection with human immunodeficiency virus is emphasized because it is increasingly common in the United States and affects the initial presentation, disease course, diagnosis, and treatment of syphilis. Of particular consequence is the effect of human immunodeficiency virus on the clinical diagnosis, prevalence, and course of neurosyphilis, one of the most serious consequences of syphilis infection.
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U2 - 10.4065/82.9.1091
DO - 10.4065/82.9.1091
M3 - Review article
AN - SCOPUS:34548451522
SN - 0025-6196
VL - 82
SP - 1091
EP - 1102
JO - Mayo Clinic Proceedings
JF - Mayo Clinic Proceedings
IS - 9
ER -