Systematic Review of Interventions to Repair Ascending Aortic Pseudoaneurysms

Henry C. Quevedo, Ricardo Santiago-Trinidad, Jorge Castellanos, Kimberly Calica Atianzar, Asif Anwar, Nidal Abi Rafeh

Research output: Contribution to journalArticle

15 Citations (Scopus)

Abstract

Background: The safety and efficacy of endovascular therapies for ascending aortic pseudoaneurysms (AAPs) are still controversial.

Methods: We report an endovascular correction of an AAP in a high-risk surgical patient and present the results of a literature review focusing on AAP treatment strategies. A multilingual search of AAP therapy was performed with limiting dates of January 1980 to May 2014. The studies were classified by intervention.

Results: A 79-year-old male with a 9×10×37 cm AAP in the anterior mediastinum was considered too high risk for surgery. An endovascular closure with a 12 mm Amplatzer septal occluder device (St. Jude Medical) was performed, and computed tomography angiography at 3-month follow-up exhibited a thrombosed AAP with minimal residual shunt. In our literature search, we identified 355 cases of AAPs, mostly case reports (91.5%) and a few patient series (8.5%). Surgical correction accounted for 73.8% of the cases, 5% of the patients were conservatively treated or considered too critically ill for any intervention, and 21.2% were treated with endovascular techniques. The most commonly reported endovascular techniques were stent grafts (9.8%) and septal occluder devices (9.8%).

Conclusion: Although endovascular closure of AAPs with offlabel devices is a reliable option for controlling the expansion and symptoms in high-risk surgical patients, solid data on survival are lacking. Efforts to promote discussion within the heart team to expand the application of endovascular techniques can provide groundbreaking evidence to support the use of endovascular techniques as guideline therapy when facing these complicated cases.

Original languageEnglish (US)
Pages (from-to)576-585
Number of pages10
JournalOchsner Journal
Volume14
Issue number4
StatePublished - Jan 1 2014
Externally publishedYes

Fingerprint

False Aneurysm
Endovascular Procedures
Septal Occluder Device
Mediastinum
Therapeutics
Critical Illness
Stents
Thrombosis
Guidelines
Transplants
Safety
Equipment and Supplies
Survival

Keywords

  • Aneurysm-false
  • Aorta
  • Endovascular procedures
  • Septal occluder device

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Quevedo, H. C., Santiago-Trinidad, R., Castellanos, J., Atianzar, K. C., Anwar, A., & Rafeh, N. A. (2014). Systematic Review of Interventions to Repair Ascending Aortic Pseudoaneurysms. Ochsner Journal, 14(4), 576-585.

Systematic Review of Interventions to Repair Ascending Aortic Pseudoaneurysms. / Quevedo, Henry C.; Santiago-Trinidad, Ricardo; Castellanos, Jorge; Atianzar, Kimberly Calica; Anwar, Asif; Rafeh, Nidal Abi.

In: Ochsner Journal, Vol. 14, No. 4, 01.01.2014, p. 576-585.

Research output: Contribution to journalArticle

Quevedo, HC, Santiago-Trinidad, R, Castellanos, J, Atianzar, KC, Anwar, A & Rafeh, NA 2014, 'Systematic Review of Interventions to Repair Ascending Aortic Pseudoaneurysms', Ochsner Journal, vol. 14, no. 4, pp. 576-585.
Quevedo HC, Santiago-Trinidad R, Castellanos J, Atianzar KC, Anwar A, Rafeh NA. Systematic Review of Interventions to Repair Ascending Aortic Pseudoaneurysms. Ochsner Journal. 2014 Jan 1;14(4):576-585.
Quevedo, Henry C. ; Santiago-Trinidad, Ricardo ; Castellanos, Jorge ; Atianzar, Kimberly Calica ; Anwar, Asif ; Rafeh, Nidal Abi. / Systematic Review of Interventions to Repair Ascending Aortic Pseudoaneurysms. In: Ochsner Journal. 2014 ; Vol. 14, No. 4. pp. 576-585.
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