Systemic effects of intraligamental injections

David Henry Pashley

Research output: Contribution to journalArticle

9 Citations (Scopus)

Abstract

Using a pistol-grip syringe, 0.3 ml of normal saline solution, 2% lidocaine with and without 1:100,000 epinephrine, 3% mepivicaine, and 1:100,000 epinephrine alone were injected into large adult dogs. The intravenous, intraosseous, intrapulpal, subcutaneous, periodontal, intramuscular, and submucosal routes were used. Changes in heart rate, blood pressure, and respiration were recorded in relation to the time of injection. In the quantities injected, normal saline solution, 2% lidocaine, and 3% mepivicaine had no measurable effect on the systemic parameters, regardless of the site of injection. Injection of 2% lidocaine with epinephrine and of epinephrine alone caused transient decreases in blood pressure and increases in heart rate. The results were similar, whether the injections were done intravenously, intraosseously, or periodontally. Systemic changes were not detected when the epinephrine-containing agents were injected intramuscularly, subcutaneously, submucosally, or intrapulpally. These results support the contention that the periodontal injection is intraosseous in nature and that solutions injected by the periodontal technique are rapidly absorbed into the systemic circulation.

Original languageEnglish (US)
Pages (from-to)501-504
Number of pages4
JournalJournal of Endodontics
Volume12
Issue number10
DOIs
StatePublished - Jan 1 1986

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Epinephrine
Lidocaine
Injections
Sodium Chloride
Heart Rate
Blood Pressure
Syringes
Hand Strength
Respiration
Dogs

ASJC Scopus subject areas

  • Dentistry(all)

Cite this

Systemic effects of intraligamental injections. / Pashley, David Henry.

In: Journal of Endodontics, Vol. 12, No. 10, 01.01.1986, p. 501-504.

Research output: Contribution to journalArticle

Pashley, David Henry. / Systemic effects of intraligamental injections. In: Journal of Endodontics. 1986 ; Vol. 12, No. 10. pp. 501-504.
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