TY - JOUR
T1 - Takotsubo cardiomyopathy
T2 - A comprehensive review
AU - Barmore, Walker
AU - Patel, Himax
AU - Harrell, Sean
AU - Garcia, Daniel
AU - Calkins, Joe B.
N1 - Funding Information:
Supported by the Gordon Chason Miller M.D. Cardiology Education Endowment Fund in the Medical College of
Publisher Copyright:
© The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved.
PY - 2022/6/1
Y1 - 2022/6/1
N2 - Takotsubo cardiomyopathy (TCM), also known as stress cardiomyopathy, occurs in the setting of catecholamine surge from an acute stressor. This cardiomyopathy mimics acute myocardial infarction in the absence of coronary disease. The classic feature of TCM is regional wall motion abnormalities with characteristic ballooning of the left ventricle. The etiology of the stressor is often physical or emotional stress, however iatrogenic causes of TCM have been reported in the literature. In our review, we discuss medications, primarily the exogenous administration of catecholamines, and a wide array of procedures with subsequent development of iatrogenic cardiomyopathy. TCM is unique in that it is transient and has favorable outcomes in most individuals. Classically, beta-blockers and ACE-inhibitors have been prescribed in individuals with cardiomyopathy; however, unique to TCM, no specific treatment is required other than temporary supportive measures as this process is transient. Additionally, no improvement in mortality or recurrence have been reported in patients on these drugs. The aim of this review is to elucidate on the iatrogenic causes of TCM, allowing for prompt recognition and management by clinicians.
AB - Takotsubo cardiomyopathy (TCM), also known as stress cardiomyopathy, occurs in the setting of catecholamine surge from an acute stressor. This cardiomyopathy mimics acute myocardial infarction in the absence of coronary disease. The classic feature of TCM is regional wall motion abnormalities with characteristic ballooning of the left ventricle. The etiology of the stressor is often physical or emotional stress, however iatrogenic causes of TCM have been reported in the literature. In our review, we discuss medications, primarily the exogenous administration of catecholamines, and a wide array of procedures with subsequent development of iatrogenic cardiomyopathy. TCM is unique in that it is transient and has favorable outcomes in most individuals. Classically, beta-blockers and ACE-inhibitors have been prescribed in individuals with cardiomyopathy; however, unique to TCM, no specific treatment is required other than temporary supportive measures as this process is transient. Additionally, no improvement in mortality or recurrence have been reported in patients on these drugs. The aim of this review is to elucidate on the iatrogenic causes of TCM, allowing for prompt recognition and management by clinicians.
KW - Cardiomyopathy
KW - Heart Failure
KW - Iatrogenic
KW - Myocardial Infarction
KW - Takotsubo
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U2 - 10.4330/wjc.v14.i6.355
DO - 10.4330/wjc.v14.i6.355
M3 - Review article
AN - SCOPUS:85133352133
SN - 1949-8462
VL - 14
SP - 355
EP - 362
JO - World Journal of Cardiology
JF - World Journal of Cardiology
IS - 6
ER -