targetHub: A programmable interface for miRNA-gene interactions

Ganiraju Manyam, Cristina Ivan, George A. Calin, Kevin R. Coombes

Research output: Contribution to journalArticlepeer-review

13 Scopus citations

Abstract

Motivation: With the expansion of high-throughput technologies, understanding different kinds of genome-level data is a common task. MicroRNA (miRNA) is increasingly profiled using high-throughput technologies (microarrays or next-generation sequencing). The downstream analysis of miRNA targets can be difficult. Although there are many databases and algorithms to predict miRNA targets, there are few tools to integrate miRNA-gene interaction data into high-throughput genomic analyses. Results:We present targetHub, a CouchDB database of miRNA-gene interactions. TargetHub provides a programmer-friendly interface to access miRNA targets. The Web site provides RESTful access to miRNA-gene interactions with an assortment of gene and miRNA identifiers. It can be a useful tool to integrate miRNA target interaction data directly into high-throughput bioinformatics analyses. Availability: TargetHub is available on the web at http://app1.bioinfor matics.mdanderson.org/tarhub/-design/basic/ index.html. Contact: coombes.3@osu.edu.

Original languageEnglish (US)
Pages (from-to)2657-2658
Number of pages2
JournalBioinformatics
Volume29
Issue number20
DOIs
StatePublished - Oct 15 2013
Externally publishedYes

ASJC Scopus subject areas

  • Statistics and Probability
  • Biochemistry
  • Molecular Biology
  • Computer Science Applications
  • Computational Theory and Mathematics
  • Computational Mathematics

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