Technical Report: Transmissible spongiform encephalopathies: A review for pediatricians

J. S. Abramson; C. J. Baker; M. C. Fisher; M. A. Gerber; H. C. Meissner; Dennis L Murray; G. D. Overturf; C. G. Prober; M. B. Rennels; T. N. Saari; L. B. Weiner; R. J. Whitley; G. Peter; L. K. Pickering; N. E. Macdonald; L. Chilton; G. Delage; S. F. Dowell; R. F. Jacobs; M. G. Myers; W. A. Orenstein; P. A. Patriarca; E. O. Ledbetter; J. Kim

Technical Report: Transmissible spongiform encephalopathies: A review for pediatricians

J. S. Abramson, C. J. Baker, M. C. Fisher, M. A. Gerber, H. C. Meissner, Dennis L Murray, G. D. Overturf, C. G. Prober, M. B. Rennels, T. N. Saari, L. B. Weiner, R. J. Whitley, G. Peter, L. K. Pickering, N. E. Macdonald, L. Chilton, G. Delage, S. F. Dowell, R. F. Jacobs, M. G. MyersW. A. Orenstein, P. A. Patriarca, E. O. Ledbetter, J. Kim

Pediatrics

Research output: Contribution to journal › Review article › peer-review

6 Scopus citations

Abstract

Transmissible spongiform encephalopathies (TSEs) are a family of rare, slowly progressive, and universally fatal neurodegenerative syndromes affecting animals and humans. Until recently, TSEs were of little interest to pediatricians. However, since the outbreak in adolescents and the association of TSEs with new-variant Creutzfeldt-Jakob disease (nvCJD), interest among pediatricians and the general public has increased. Even before bovine spongiform encephalopathy and nvCJD were linked, the recognition that iatrogenic Creutzfeldt-Jakob disease (CJD) had been acquired from administration of cadaveric human growth and gonadotropic hormones and from corneal and dura mater transplants prompted medical vigilance. Furthermore, recent concern about the potential for transmission of CJD by blood and blood products has raised awareness among public health and regulatory agencies, pediatricians, and the public, although no epidemiologic data support this concern. Because of worldwide concern (although no cases have been reported in North America), this review focuses on the potential impact of TSEs, particularly CJD and nvCJD, on the pediatric population.

Original language	English (US)
Pages (from-to)	1160-1165
Number of pages	6
Journal	Pediatrics
Volume	106
Issue number	5 I
State	Published - 2000

ASJC Scopus subject areas

Pediatrics, Perinatology, and Child Health

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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Abramson, J. S., Baker, C. J., Fisher, M. C., Gerber, M. A., Meissner, H. C., Murray, D. L., Overturf, G. D., Prober, C. G., Rennels, M. B., Saari, T. N., Weiner, L. B., Whitley, R. J., Peter, G., Pickering, L. K., Macdonald, N. E., Chilton, L., Delage, G., Dowell, S. F., Jacobs, R. F., ... Kim, J. (2000). Technical Report: Transmissible spongiform encephalopathies: A review for pediatricians. Pediatrics, 106(5 I), 1160-1165.

Abramson, JS, Baker, CJ, Fisher, MC, Gerber, MA, Meissner, HC, Murray, DL, Overturf, GD, Prober, CG, Rennels, MB, Saari, TN, Weiner, LB, Whitley, RJ, Peter, G, Pickering, LK, Macdonald, NE, Chilton, L, Delage, G, Dowell, SF, Jacobs, RF, Myers, MG, Orenstein, WA, Patriarca, PA, Ledbetter, EO & Kim, J 2000, 'Technical Report: Transmissible spongiform encephalopathies: A review for pediatricians', Pediatrics, vol. 106, no. 5 I, pp. 1160-1165.

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abstract = "Transmissible spongiform encephalopathies (TSEs) are a family of rare, slowly progressive, and universally fatal neurodegenerative syndromes affecting animals and humans. Until recently, TSEs were of little interest to pediatricians. However, since the outbreak in adolescents and the association of TSEs with new-variant Creutzfeldt-Jakob disease (nvCJD), interest among pediatricians and the general public has increased. Even before bovine spongiform encephalopathy and nvCJD were linked, the recognition that iatrogenic Creutzfeldt-Jakob disease (CJD) had been acquired from administration of cadaveric human growth and gonadotropic hormones and from corneal and dura mater transplants prompted medical vigilance. Furthermore, recent concern about the potential for transmission of CJD by blood and blood products has raised awareness among public health and regulatory agencies, pediatricians, and the public, although no epidemiologic data support this concern. Because of worldwide concern (although no cases have been reported in North America), this review focuses on the potential impact of TSEs, particularly CJD and nvCJD, on the pediatric population.",

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AU - Abramson, J. S.

AU - Baker, C. J.

AU - Fisher, M. C.

AU - Gerber, M. A.

AU - Meissner, H. C.

AU - Murray, Dennis L

AU - Overturf, G. D.

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AU - Chilton, L.

AU - Delage, G.

AU - Dowell, S. F.

AU - Jacobs, R. F.

AU - Myers, M. G.

AU - Orenstein, W. A.

AU - Patriarca, P. A.

AU - Ledbetter, E. O.

AU - Kim, J.

PY - 2000

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N2 - Transmissible spongiform encephalopathies (TSEs) are a family of rare, slowly progressive, and universally fatal neurodegenerative syndromes affecting animals and humans. Until recently, TSEs were of little interest to pediatricians. However, since the outbreak in adolescents and the association of TSEs with new-variant Creutzfeldt-Jakob disease (nvCJD), interest among pediatricians and the general public has increased. Even before bovine spongiform encephalopathy and nvCJD were linked, the recognition that iatrogenic Creutzfeldt-Jakob disease (CJD) had been acquired from administration of cadaveric human growth and gonadotropic hormones and from corneal and dura mater transplants prompted medical vigilance. Furthermore, recent concern about the potential for transmission of CJD by blood and blood products has raised awareness among public health and regulatory agencies, pediatricians, and the public, although no epidemiologic data support this concern. Because of worldwide concern (although no cases have been reported in North America), this review focuses on the potential impact of TSEs, particularly CJD and nvCJD, on the pediatric population.

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Technical Report: Transmissible spongiform encephalopathies: A review for pediatricians

Abstract

ASJC Scopus subject areas

UN SDGs

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