Abstract
(Chemical Equation Presented) At the process of ethyl 6-methyl-4-aryl-2- thioxo-1,2,3,4-tetrahydropyrimidine-5-carboxylates condensation with aryl aldehydes and chloroacetic acid the unexpected formation of 5- arylidenethiazolidine-2,4-diones was determined in high yields as the reaction time was increased to 20 h. The latter represent the products of destructive hydrolyzes of ethyl 2-benzylidene-7-methyl-3-oxo-5-aryl-2,3-dihydro-5H-[1,3] thiazolo[3,2-a]pyrimidine-6-carboxylates which have been proved by independent synthesis.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 368-372 |
| Number of pages | 5 |
| Journal | Journal of Heterocyclic Chemistry |
| Volume | 47 |
| Issue number | 2 |
| DOIs | |
| State | Published - Mar 1 2010 |
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ASJC Scopus subject areas
- Organic Chemistry
Cite this
Ternary condensation of Biginelli thiones, chloroacetic acid, and aldehydes as an effective approach towards thiazolo[3,2-a] pyrimidines and 5-arylidenethiazolidine-2,4-diones. / Lebedyeva, Iryna Oleksandrivna; Povstyanoy, Mykhaylo V.; Ryabitskii, Aleksey B.; Povstyanoy, Vyacheslav M.
In: Journal of Heterocyclic Chemistry, Vol. 47, No. 2, 01.03.2010, p. 368-372.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Ternary condensation of Biginelli thiones, chloroacetic acid, and aldehydes as an effective approach towards thiazolo[3,2-a] pyrimidines and 5-arylidenethiazolidine-2,4-diones
AU - Lebedyeva, Iryna Oleksandrivna
AU - Povstyanoy, Mykhaylo V.
AU - Ryabitskii, Aleksey B.
AU - Povstyanoy, Vyacheslav M.
PY - 2010/3/1
Y1 - 2010/3/1
N2 - (Chemical Equation Presented) At the process of ethyl 6-methyl-4-aryl-2- thioxo-1,2,3,4-tetrahydropyrimidine-5-carboxylates condensation with aryl aldehydes and chloroacetic acid the unexpected formation of 5- arylidenethiazolidine-2,4-diones was determined in high yields as the reaction time was increased to 20 h. The latter represent the products of destructive hydrolyzes of ethyl 2-benzylidene-7-methyl-3-oxo-5-aryl-2,3-dihydro-5H-[1,3] thiazolo[3,2-a]pyrimidine-6-carboxylates which have been proved by independent synthesis.
AB - (Chemical Equation Presented) At the process of ethyl 6-methyl-4-aryl-2- thioxo-1,2,3,4-tetrahydropyrimidine-5-carboxylates condensation with aryl aldehydes and chloroacetic acid the unexpected formation of 5- arylidenethiazolidine-2,4-diones was determined in high yields as the reaction time was increased to 20 h. The latter represent the products of destructive hydrolyzes of ethyl 2-benzylidene-7-methyl-3-oxo-5-aryl-2,3-dihydro-5H-[1,3] thiazolo[3,2-a]pyrimidine-6-carboxylates which have been proved by independent synthesis.
UR - http://www.scopus.com/inward/record.url?scp=77950309985&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=77950309985&partnerID=8YFLogxK
U2 - 10.1002/jhet.323
DO - 10.1002/jhet.323
M3 - Article
AN - SCOPUS:77950309985
VL - 47
SP - 368
EP - 372
JO - Journal of Heterocyclic Chemistry
JF - Journal of Heterocyclic Chemistry
SN - 0022-152X
IS - 2
ER -