Testicular Blood Flow and Fluid Dynamics in Monkeys with Surgically Induced Varicoceles

RICHARD M. HARRISON, Ronald W Lewis, JAMES A. ROBERTS

Research output: Contribution to journalArticle

22 Citations (Scopus)

Abstract

The blood flow rates and ability to remove an added fluid load were studied in the testes of monkeys with surgically induced varicoceles and in sham‐operated control monkeys. These studies were conducted to verify a proposed mechanism by which varicocele may cause testicular and spermatogenic damage. Analyses of the data indicated mat, at four months after induction, the testes of monkeys with varicocele were less able to remove a perfused fluid load and that, at five months, the blood flow was significantly less in the testes of these animals. The effects were most pronounced in the left testes of the monkeys with varicocele. Blood flow values calculated were: control, right—9.66 ml × 100 g−1 × min−1; control, left—10.42 ml × 100 g−1 × min−1; varicocele, right—7.73 ml × 100 g−1 × min−1; varicocele, left—5.04 ml × 100 g−1 × min−1. These data suggest a new theory, that increased pressure on the venous side of testicular capillary beds in subjects with varicocele may decrease blood flow and cause testicular damage. 1983 American Society of Andrology

Original languageEnglish (US)
Pages (from-to)256-260
Number of pages5
JournalJournal of Andrology
Volume4
Issue number4
DOIs
StatePublished - Jan 1 1983

Fingerprint

Varicocele
Hydrodynamics
Haplorhini
Testis
Venous Pressure

Keywords

  • intratesticular tissue pressure
  • monkey
  • testicular blood flow
  • varicocele

ASJC Scopus subject areas

  • Endocrinology, Diabetes and Metabolism
  • Reproductive Medicine
  • Endocrinology
  • Urology

Cite this

Testicular Blood Flow and Fluid Dynamics in Monkeys with Surgically Induced Varicoceles. / HARRISON, RICHARD M.; Lewis, Ronald W; ROBERTS, JAMES A.

In: Journal of Andrology, Vol. 4, No. 4, 01.01.1983, p. 256-260.

Research output: Contribution to journalArticle

HARRISON, RICHARD M. ; Lewis, Ronald W ; ROBERTS, JAMES A. / Testicular Blood Flow and Fluid Dynamics in Monkeys with Surgically Induced Varicoceles. In: Journal of Andrology. 1983 ; Vol. 4, No. 4. pp. 256-260.
@article{db8018fca9dd42c18902a463826afb69,
title = "Testicular Blood Flow and Fluid Dynamics in Monkeys with Surgically Induced Varicoceles",
abstract = "The blood flow rates and ability to remove an added fluid load were studied in the testes of monkeys with surgically induced varicoceles and in sham‐operated control monkeys. These studies were conducted to verify a proposed mechanism by which varicocele may cause testicular and spermatogenic damage. Analyses of the data indicated mat, at four months after induction, the testes of monkeys with varicocele were less able to remove a perfused fluid load and that, at five months, the blood flow was significantly less in the testes of these animals. The effects were most pronounced in the left testes of the monkeys with varicocele. Blood flow values calculated were: control, right—9.66 ml × 100 g−1 × min−1; control, left—10.42 ml × 100 g−1 × min−1; varicocele, right—7.73 ml × 100 g−1 × min−1; varicocele, left—5.04 ml × 100 g−1 × min−1. These data suggest a new theory, that increased pressure on the venous side of testicular capillary beds in subjects with varicocele may decrease blood flow and cause testicular damage. 1983 American Society of Andrology",
keywords = "intratesticular tissue pressure, monkey, testicular blood flow, varicocele",
author = "HARRISON, {RICHARD M.} and Lewis, {Ronald W} and ROBERTS, {JAMES A.}",
year = "1983",
month = "1",
day = "1",
doi = "10.1002/j.1939-4640.1983.tb02363.x",
language = "English (US)",
volume = "4",
pages = "256--260",
journal = "Journal of Andrology",
issn = "0196-3635",
publisher = "American Society of Andrology Inc.",
number = "4",

}

TY - JOUR

T1 - Testicular Blood Flow and Fluid Dynamics in Monkeys with Surgically Induced Varicoceles

AU - HARRISON, RICHARD M.

AU - Lewis, Ronald W

AU - ROBERTS, JAMES A.

PY - 1983/1/1

Y1 - 1983/1/1

N2 - The blood flow rates and ability to remove an added fluid load were studied in the testes of monkeys with surgically induced varicoceles and in sham‐operated control monkeys. These studies were conducted to verify a proposed mechanism by which varicocele may cause testicular and spermatogenic damage. Analyses of the data indicated mat, at four months after induction, the testes of monkeys with varicocele were less able to remove a perfused fluid load and that, at five months, the blood flow was significantly less in the testes of these animals. The effects were most pronounced in the left testes of the monkeys with varicocele. Blood flow values calculated were: control, right—9.66 ml × 100 g−1 × min−1; control, left—10.42 ml × 100 g−1 × min−1; varicocele, right—7.73 ml × 100 g−1 × min−1; varicocele, left—5.04 ml × 100 g−1 × min−1. These data suggest a new theory, that increased pressure on the venous side of testicular capillary beds in subjects with varicocele may decrease blood flow and cause testicular damage. 1983 American Society of Andrology

AB - The blood flow rates and ability to remove an added fluid load were studied in the testes of monkeys with surgically induced varicoceles and in sham‐operated control monkeys. These studies were conducted to verify a proposed mechanism by which varicocele may cause testicular and spermatogenic damage. Analyses of the data indicated mat, at four months after induction, the testes of monkeys with varicocele were less able to remove a perfused fluid load and that, at five months, the blood flow was significantly less in the testes of these animals. The effects were most pronounced in the left testes of the monkeys with varicocele. Blood flow values calculated were: control, right—9.66 ml × 100 g−1 × min−1; control, left—10.42 ml × 100 g−1 × min−1; varicocele, right—7.73 ml × 100 g−1 × min−1; varicocele, left—5.04 ml × 100 g−1 × min−1. These data suggest a new theory, that increased pressure on the venous side of testicular capillary beds in subjects with varicocele may decrease blood flow and cause testicular damage. 1983 American Society of Andrology

KW - intratesticular tissue pressure

KW - monkey

KW - testicular blood flow

KW - varicocele

UR - http://www.scopus.com/inward/record.url?scp=0020792001&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0020792001&partnerID=8YFLogxK

U2 - 10.1002/j.1939-4640.1983.tb02363.x

DO - 10.1002/j.1939-4640.1983.tb02363.x

M3 - Article

C2 - 6618996

AN - SCOPUS:0020792001

VL - 4

SP - 256

EP - 260

JO - Journal of Andrology

JF - Journal of Andrology

SN - 0196-3635

IS - 4

ER -