The appropriate use of skin testing and allergen immunotherapy in young children

Dennis Randall Ownby, Allen D. Adinoff

Research output: Contribution to journalArticle

46 Citations (Scopus)

Abstract

Immunotherapy is clearly effective in the treatment of allergic rhinitis and Hymenoptera sensitivity and probably effective in the treatment of asthma. Few studies evaluate the risks and benefits of immunotherapy in young children. Current evidence suggests that young children are at increased risk for systemic reactions from immunotherapy. Furthermore, immunotherapy or adverse reactions resulting from immunotherapy may result in significant psychologic problems. The potential risks of immunotherapy would be justified if immunotherapy were demonstrated to be safe and additive to other therapies. Immunotherapy might be particularly effective in treating or helping to prevent house dust mite- or cockroach-associated asthma. Until the efficacy of immunotherapy is demonstrated in young children, we agree with the European Academy of Allergology and Clinical Immunology position that immunotherapy in young children is relatively contraindicated.

Original languageEnglish (US)
Pages (from-to)662-665
Number of pages4
JournalThe Journal of Allergy and Clinical Immunology
Volume94
Issue number4
DOIs
StatePublished - Jan 1 1994

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Immunologic Desensitization
Immunotherapy
Skin
Asthma
Pyroglyphidae
Cockroaches
Hymenoptera
Therapeutics

ASJC Scopus subject areas

  • Immunology and Allergy
  • Immunology

Cite this

The appropriate use of skin testing and allergen immunotherapy in young children. / Ownby, Dennis Randall; Adinoff, Allen D.

In: The Journal of Allergy and Clinical Immunology, Vol. 94, No. 4, 01.01.1994, p. 662-665.

Research output: Contribution to journalArticle

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