The Brn-3a transcription factor gene (POU4F1) maps close to the locus for the variant late infantile form of neuronal ceroid-lipofuscinosis

I. H. Still; J. Cowell

doi:10.1159/000134422

The Brn-3a transcription factor gene (POU4F1) maps close to the locus for the variant late infantile form of neuronal ceroid-lipofuscinosis

I. H. Still, J. Cowell

Research output: Contribution to journal › Article › peer-review

1 Scopus citations

Abstract

We have refined the location of the Brn-3a genomic locus (POU4F1), using somatic cell hybrid analysis, to 13q21.→q22. Furthermore, we have shown that two YACs, known to contain the closest marker linked to neuronal ceroidlipofuscinosis (CLN5), also contains the Brn-3a gene. As one of these YACs is only 320 kb long, this localises POU4F1 within the critical region defining the CLN5 locus, and raises the possibility that POU4F1 is a candidate gene for CLN5.

Original language	English (US)
Pages (from-to)	225-226
Number of pages	2
Journal	Cytogenetic and Genome Research
Volume	74
Issue number	3
DOIs	https://doi.org/10.1159/000134422
State	Published - Jan 1 1996
Externally published	Yes

ASJC Scopus subject areas

Molecular Biology
Genetics
Genetics(clinical)

Access to Document

10.1159/000134422

Cite this

@article{dab2f374e8d440219e1dbdb528fb52d8,

title = "The Brn-3a transcription factor gene (POU4F1) maps close to the locus for the variant late infantile form of neuronal ceroid-lipofuscinosis",

abstract = "We have refined the location of the Brn-3a genomic locus (POU4F1), using somatic cell hybrid analysis, to 13q21.→q22. Furthermore, we have shown that two YACs, known to contain the closest marker linked to neuronal ceroidlipofuscinosis (CLN5), also contains the Brn-3a gene. As one of these YACs is only 320 kb long, this localises POU4F1 within the critical region defining the CLN5 locus, and raises the possibility that POU4F1 is a candidate gene for CLN5.",

author = "Still, {I. H.} and J. Cowell",

year = "1996",

month = jan,

day = "1",

doi = "10.1159/000134422",

language = "English (US)",

volume = "74",

pages = "225--226",

journal = "Cytogenetic and Genome Research",

issn = "1424-8581",

publisher = "S. Karger AG",

number = "3",

}

TY - JOUR

T1 - The Brn-3a transcription factor gene (POU4F1) maps close to the locus for the variant late infantile form of neuronal ceroid-lipofuscinosis

AU - Still, I. H.

AU - Cowell, J.

PY - 1996/1/1

Y1 - 1996/1/1

N2 - We have refined the location of the Brn-3a genomic locus (POU4F1), using somatic cell hybrid analysis, to 13q21.→q22. Furthermore, we have shown that two YACs, known to contain the closest marker linked to neuronal ceroidlipofuscinosis (CLN5), also contains the Brn-3a gene. As one of these YACs is only 320 kb long, this localises POU4F1 within the critical region defining the CLN5 locus, and raises the possibility that POU4F1 is a candidate gene for CLN5.

AB - We have refined the location of the Brn-3a genomic locus (POU4F1), using somatic cell hybrid analysis, to 13q21.→q22. Furthermore, we have shown that two YACs, known to contain the closest marker linked to neuronal ceroidlipofuscinosis (CLN5), also contains the Brn-3a gene. As one of these YACs is only 320 kb long, this localises POU4F1 within the critical region defining the CLN5 locus, and raises the possibility that POU4F1 is a candidate gene for CLN5.

UR - http://www.scopus.com/inward/record.url?scp=0029842917&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0029842917&partnerID=8YFLogxK

U2 - 10.1159/000134422

DO - 10.1159/000134422

M3 - Article

C2 - 8941380

AN - SCOPUS:0029842917

VL - 74

SP - 225

EP - 226

JO - Cytogenetic and Genome Research

JF - Cytogenetic and Genome Research

SN - 1424-8581

IS - 3

ER -

The Brn-3a transcription factor gene (POU4F1) maps close to the locus for the variant late infantile form of neuronal ceroid-lipofuscinosis

Abstract

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this