Abstract
Introduction: This study examined the ability of two versions of QMix, an experimental antimicrobial irrigant, on removal of canal wall smear layers and debris using an open canal design. Methods: Cleaned and shaped single-rooted human root canals were irrigated with NaOCl as the initial irrigant and one of the following as the final irrigant: (1) QMix I (pH = 8), (2) QMix II (pH = 7.5), (3) distilled water, (4) 17% EDTA, and (5) BioPure MTAD (Dentsply Tulsa Dental Specialties, Tulsa, OK). Smear and debris scores were evaluated in the coronal, middle, and apical thirds of longitudinally fractured canal spaces using scanning electron microscopy and analyzed using Cochran-Mantel-Haenszel statistic. Results: Smear scores, when the overall canal was considered, differences were observed among groups except groups 1 versus 4 and groups 2 versus 4. After adjusting for canal levels, all groups differed significantly from each other (p < 0.005) with the exception of groups 2 versus 5. For the debris scores, no significant difference was observed among the treatment groups when the overall canal was considered and after adjusting for the effect of canal level. Conclusion: Within the limitations of an open-canal design, the two experimental QMix versions are as effective as 17% EDTA in removing canal wall smear layers after the use of 5.25% NaOCl as the initial rinse.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 80-84 |
| Number of pages | 5 |
| Journal | Journal of Endodontics |
| Volume | 37 |
| Issue number | 1 |
| DOIs | |
| State | Published - Jan 1 2011 |
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Keywords
- Antimicrobial
- canal level
- chelation
- debris
- root canal irrigant
- smear layer
- surfactant
ASJC Scopus subject areas
- Dentistry(all)
Cite this
The effect of QMix, an experimental antibacterial root canal irrigant, on removal of canal wall smear layer and debris. / Dai, Lin; Khechen, Khaled; Khan, Sara; Gillen, Brian; Loushine, Bethany A.; Wimmer, Courtney E.; Gutmann, James L.; Pashley, David Henry; Tay, Franklin Chi Meng.
In: Journal of Endodontics, Vol. 37, No. 1, 01.01.2011, p. 80-84.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - The effect of QMix, an experimental antibacterial root canal irrigant, on removal of canal wall smear layer and debris
AU - Dai, Lin
AU - Khechen, Khaled
AU - Khan, Sara
AU - Gillen, Brian
AU - Loushine, Bethany A.
AU - Wimmer, Courtney E.
AU - Gutmann, James L.
AU - Pashley, David Henry
AU - Tay, Franklin Chi Meng
PY - 2011/1/1
Y1 - 2011/1/1
N2 - Introduction: This study examined the ability of two versions of QMix, an experimental antimicrobial irrigant, on removal of canal wall smear layers and debris using an open canal design. Methods: Cleaned and shaped single-rooted human root canals were irrigated with NaOCl as the initial irrigant and one of the following as the final irrigant: (1) QMix I (pH = 8), (2) QMix II (pH = 7.5), (3) distilled water, (4) 17% EDTA, and (5) BioPure MTAD (Dentsply Tulsa Dental Specialties, Tulsa, OK). Smear and debris scores were evaluated in the coronal, middle, and apical thirds of longitudinally fractured canal spaces using scanning electron microscopy and analyzed using Cochran-Mantel-Haenszel statistic. Results: Smear scores, when the overall canal was considered, differences were observed among groups except groups 1 versus 4 and groups 2 versus 4. After adjusting for canal levels, all groups differed significantly from each other (p < 0.005) with the exception of groups 2 versus 5. For the debris scores, no significant difference was observed among the treatment groups when the overall canal was considered and after adjusting for the effect of canal level. Conclusion: Within the limitations of an open-canal design, the two experimental QMix versions are as effective as 17% EDTA in removing canal wall smear layers after the use of 5.25% NaOCl as the initial rinse.
AB - Introduction: This study examined the ability of two versions of QMix, an experimental antimicrobial irrigant, on removal of canal wall smear layers and debris using an open canal design. Methods: Cleaned and shaped single-rooted human root canals were irrigated with NaOCl as the initial irrigant and one of the following as the final irrigant: (1) QMix I (pH = 8), (2) QMix II (pH = 7.5), (3) distilled water, (4) 17% EDTA, and (5) BioPure MTAD (Dentsply Tulsa Dental Specialties, Tulsa, OK). Smear and debris scores were evaluated in the coronal, middle, and apical thirds of longitudinally fractured canal spaces using scanning electron microscopy and analyzed using Cochran-Mantel-Haenszel statistic. Results: Smear scores, when the overall canal was considered, differences were observed among groups except groups 1 versus 4 and groups 2 versus 4. After adjusting for canal levels, all groups differed significantly from each other (p < 0.005) with the exception of groups 2 versus 5. For the debris scores, no significant difference was observed among the treatment groups when the overall canal was considered and after adjusting for the effect of canal level. Conclusion: Within the limitations of an open-canal design, the two experimental QMix versions are as effective as 17% EDTA in removing canal wall smear layers after the use of 5.25% NaOCl as the initial rinse.
KW - Antimicrobial
KW - canal level
KW - chelation
KW - debris
KW - root canal irrigant
KW - smear layer
KW - surfactant
UR - http://www.scopus.com/inward/record.url?scp=78650121819&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=78650121819&partnerID=8YFLogxK
U2 - 10.1016/j.joen.2010.10.004
DO - 10.1016/j.joen.2010.10.004
M3 - Article
VL - 37
SP - 80
EP - 84
JO - Journal of Endodontics
JF - Journal of Endodontics
SN - 0099-2399
IS - 1
ER -