The effect of QMix, an experimental antibacterial root canal irrigant, on removal of canal wall smear layer and debris

Lin Dai, Khaled Khechen, Sara Khan, Brian Gillen, Bethany A. Loushine, Courtney E. Wimmer, James L. Gutmann, David Henry Pashley, Franklin Chi Meng Tay

Research output: Contribution to journalArticle

86 Citations (Scopus)

Abstract

Introduction: This study examined the ability of two versions of QMix, an experimental antimicrobial irrigant, on removal of canal wall smear layers and debris using an open canal design. Methods: Cleaned and shaped single-rooted human root canals were irrigated with NaOCl as the initial irrigant and one of the following as the final irrigant: (1) QMix I (pH = 8), (2) QMix II (pH = 7.5), (3) distilled water, (4) 17% EDTA, and (5) BioPure MTAD (Dentsply Tulsa Dental Specialties, Tulsa, OK). Smear and debris scores were evaluated in the coronal, middle, and apical thirds of longitudinally fractured canal spaces using scanning electron microscopy and analyzed using Cochran-Mantel-Haenszel statistic. Results: Smear scores, when the overall canal was considered, differences were observed among groups except groups 1 versus 4 and groups 2 versus 4. After adjusting for canal levels, all groups differed significantly from each other (p < 0.005) with the exception of groups 2 versus 5. For the debris scores, no significant difference was observed among the treatment groups when the overall canal was considered and after adjusting for the effect of canal level. Conclusion: Within the limitations of an open-canal design, the two experimental QMix versions are as effective as 17% EDTA in removing canal wall smear layers after the use of 5.25% NaOCl as the initial rinse.

Original languageEnglish (US)
Pages (from-to)80-84
Number of pages5
JournalJournal of Endodontics
Volume37
Issue number1
DOIs
StatePublished - Jan 1 2011

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Root Canal Irrigants
Smear Layer
Edetic Acid
Dental Specialties
Dental Pulp Cavity
Electron Scanning Microscopy
Research Design
Water

Keywords

  • Antimicrobial
  • canal level
  • chelation
  • debris
  • root canal irrigant
  • smear layer
  • surfactant

ASJC Scopus subject areas

  • Dentistry(all)

Cite this

The effect of QMix, an experimental antibacterial root canal irrigant, on removal of canal wall smear layer and debris. / Dai, Lin; Khechen, Khaled; Khan, Sara; Gillen, Brian; Loushine, Bethany A.; Wimmer, Courtney E.; Gutmann, James L.; Pashley, David Henry; Tay, Franklin Chi Meng.

In: Journal of Endodontics, Vol. 37, No. 1, 01.01.2011, p. 80-84.

Research output: Contribution to journalArticle

Dai, L, Khechen, K, Khan, S, Gillen, B, Loushine, BA, Wimmer, CE, Gutmann, JL, Pashley, DH & Tay, FCM 2011, 'The effect of QMix, an experimental antibacterial root canal irrigant, on removal of canal wall smear layer and debris', Journal of Endodontics, vol. 37, no. 1, pp. 80-84. https://doi.org/10.1016/j.joen.2010.10.004
Dai, Lin ; Khechen, Khaled ; Khan, Sara ; Gillen, Brian ; Loushine, Bethany A. ; Wimmer, Courtney E. ; Gutmann, James L. ; Pashley, David Henry ; Tay, Franklin Chi Meng. / The effect of QMix, an experimental antibacterial root canal irrigant, on removal of canal wall smear layer and debris. In: Journal of Endodontics. 2011 ; Vol. 37, No. 1. pp. 80-84.
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AU - Wimmer, Courtney E.

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AB - Introduction: This study examined the ability of two versions of QMix, an experimental antimicrobial irrigant, on removal of canal wall smear layers and debris using an open canal design. Methods: Cleaned and shaped single-rooted human root canals were irrigated with NaOCl as the initial irrigant and one of the following as the final irrigant: (1) QMix I (pH = 8), (2) QMix II (pH = 7.5), (3) distilled water, (4) 17% EDTA, and (5) BioPure MTAD (Dentsply Tulsa Dental Specialties, Tulsa, OK). Smear and debris scores were evaluated in the coronal, middle, and apical thirds of longitudinally fractured canal spaces using scanning electron microscopy and analyzed using Cochran-Mantel-Haenszel statistic. Results: Smear scores, when the overall canal was considered, differences were observed among groups except groups 1 versus 4 and groups 2 versus 4. After adjusting for canal levels, all groups differed significantly from each other (p < 0.005) with the exception of groups 2 versus 5. For the debris scores, no significant difference was observed among the treatment groups when the overall canal was considered and after adjusting for the effect of canal level. Conclusion: Within the limitations of an open-canal design, the two experimental QMix versions are as effective as 17% EDTA in removing canal wall smear layers after the use of 5.25% NaOCl as the initial rinse.

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