The effects of maternal hyperoxia on fetal breathing movements in third-trimester pregnancies

Lawrence D Devoe, Hassan Abduljabbar, Lesley Carmichael, Carol Probert, John Patrick

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

Fetal breathing movements and gross fetal body movements were observed before, during, and after maternal hyperoxia induced by inhalation of 50% oxygen in 14 women with normal term pregnancies. Studies were performed with real-time B-scan linear-array ultrasound and were standardized for time of day, maternal nutritional status, postprandial interval, and length of observation. Each study included a 30-minute baseline, followed by 15 minutes of hyperoxia, and 45 minutes of continued monitoring. No significant changes occurred in the mean incidences of fetal breathing movements, gross fetal body movements, the mean breathing rate, or breath interval variability, as analyzed in 5-minute epochs. Maternal Po2, as measured by transcutaneous electrodes, increased to the maximum level after 5 minutes of hyperoxia (155% over control levels). The breathing activity of normal third-trimester fetuses appears to be stimulated maximally in the second and third postprandial hours and cannot be further increased by maternal hyperoxia. This protocol represents a possible clinical strategy for investigating fetuses at risk for intrauterine hypoxia, provided that similar experimental conditions are maintained.

Original languageEnglish (US)
Pages (from-to)790-794
Number of pages5
JournalAmerican Journal of Obstetrics and Gynecology
Volume148
Issue number6
DOIs
StatePublished - Mar 15 1984
Externally publishedYes

Fingerprint

Fetal Movement
Hyperoxia
Third Pregnancy Trimester
Respiration
Mothers
Fetus
Nutritional Status
Inhalation
Electrodes
Observation
Oxygen
Pregnancy
Incidence

ASJC Scopus subject areas

  • Medicine(all)
  • Obstetrics and Gynecology

Cite this

The effects of maternal hyperoxia on fetal breathing movements in third-trimester pregnancies. / Devoe, Lawrence D; Abduljabbar, Hassan; Carmichael, Lesley; Probert, Carol; Patrick, John.

In: American Journal of Obstetrics and Gynecology, Vol. 148, No. 6, 15.03.1984, p. 790-794.

Research output: Contribution to journalArticle

Devoe, Lawrence D ; Abduljabbar, Hassan ; Carmichael, Lesley ; Probert, Carol ; Patrick, John. / The effects of maternal hyperoxia on fetal breathing movements in third-trimester pregnancies. In: American Journal of Obstetrics and Gynecology. 1984 ; Vol. 148, No. 6. pp. 790-794.
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