The Effects of Obesity, Gender, and Ethnic Group on Left Ventricular Hypertrophy and Geometry in Hypertensive Children

A Collaborative Study of the International Pediatric Hypertension Association

Coral Hanevold, Jennifer L Waller, Stephen Daniels, Ronald Portman, Jonathan Sorof

Research output: Contribution to journalReview article

250 Citations (Scopus)

Abstract

Objective. To determine the prevalence of left ventricular hypertrophy (LVH) in a multiethnic group of children and adolescents with hypertension. Design/Methods. Pooled data from 1998 to 2001 from 3 sites belonging to the International Pediatric Hypertension Association were reviewed. Patients undergoing echocardiography to detect LVH as part of the evaluation for hypertension were included for analysis. Left ventricular mass was calculated from 2-dimensional guided M-mode echocardiographic measurements of the left ventricle. Left ventricular mass index (LVMI) was calculated as left ventricular mass/height2.7. LVH by adult criteria was defined as LVMI > 51 g/m2.7 and by pediatric criteria as LVMI > 38.6 g/m2.7. Left ventricle geometry was classified as concentric, concentric remodeling, eccentric, or normal. Results. Data on 129 patients with a mean age of 13.6 ± 3.6 years were analyzed. The population was 67% male, 46.5% white, 38.0% African American, and 15.5% Hispanic. The prevalence of LVH was 15.5% using adult criteria and 41.1% using pediatric criteria. Increasing body mass index (BMI) was associated with a higher LVMI. Using either pediatric or adult criteria LVH was associated with BMI ≥95th percentile for age and gender. LVH and concentric hypertrophy were identified most frequently in Hispanic children. Conclusions. LVH occurs commonly in children with hypertension and is associated with an increased BMI. LVH may be more prevalent in Hispanic children than in other ethnic groups. Prevention and treatment of obesity is important in reducing the cardiovascular risk for children with hypertension. Further evaluation of the frequency of LVH in multiethnic populations is needed.

Original languageEnglish (US)
Pages (from-to)328-333
Number of pages6
JournalPediatrics
Volume113
Issue number2
DOIs
StatePublished - Feb 1 2004

Fingerprint

Left Ventricular Hypertrophy
Ethnic Groups
Obesity
Pediatrics
Hypertension
Hispanic Americans
Body Mass Index
Heart Ventricles
African Americans
Hypertrophy
Population
Echocardiography

Keywords

  • Children
  • Echocardiography
  • Hypertension
  • Left ventricular hypertrophy
  • Obesity

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health

Cite this

The Effects of Obesity, Gender, and Ethnic Group on Left Ventricular Hypertrophy and Geometry in Hypertensive Children : A Collaborative Study of the International Pediatric Hypertension Association. / Hanevold, Coral; Waller, Jennifer L; Daniels, Stephen; Portman, Ronald; Sorof, Jonathan.

In: Pediatrics, Vol. 113, No. 2, 01.02.2004, p. 328-333.

Research output: Contribution to journalReview article

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title = "The Effects of Obesity, Gender, and Ethnic Group on Left Ventricular Hypertrophy and Geometry in Hypertensive Children: A Collaborative Study of the International Pediatric Hypertension Association",
abstract = "Objective. To determine the prevalence of left ventricular hypertrophy (LVH) in a multiethnic group of children and adolescents with hypertension. Design/Methods. Pooled data from 1998 to 2001 from 3 sites belonging to the International Pediatric Hypertension Association were reviewed. Patients undergoing echocardiography to detect LVH as part of the evaluation for hypertension were included for analysis. Left ventricular mass was calculated from 2-dimensional guided M-mode echocardiographic measurements of the left ventricle. Left ventricular mass index (LVMI) was calculated as left ventricular mass/height2.7. LVH by adult criteria was defined as LVMI > 51 g/m2.7 and by pediatric criteria as LVMI > 38.6 g/m2.7. Left ventricle geometry was classified as concentric, concentric remodeling, eccentric, or normal. Results. Data on 129 patients with a mean age of 13.6 ± 3.6 years were analyzed. The population was 67{\%} male, 46.5{\%} white, 38.0{\%} African American, and 15.5{\%} Hispanic. The prevalence of LVH was 15.5{\%} using adult criteria and 41.1{\%} using pediatric criteria. Increasing body mass index (BMI) was associated with a higher LVMI. Using either pediatric or adult criteria LVH was associated with BMI ≥95th percentile for age and gender. LVH and concentric hypertrophy were identified most frequently in Hispanic children. Conclusions. LVH occurs commonly in children with hypertension and is associated with an increased BMI. LVH may be more prevalent in Hispanic children than in other ethnic groups. Prevention and treatment of obesity is important in reducing the cardiovascular risk for children with hypertension. Further evaluation of the frequency of LVH in multiethnic populations is needed.",
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T2 - A Collaborative Study of the International Pediatric Hypertension Association

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AU - Waller, Jennifer L

AU - Daniels, Stephen

AU - Portman, Ronald

AU - Sorof, Jonathan

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N2 - Objective. To determine the prevalence of left ventricular hypertrophy (LVH) in a multiethnic group of children and adolescents with hypertension. Design/Methods. Pooled data from 1998 to 2001 from 3 sites belonging to the International Pediatric Hypertension Association were reviewed. Patients undergoing echocardiography to detect LVH as part of the evaluation for hypertension were included for analysis. Left ventricular mass was calculated from 2-dimensional guided M-mode echocardiographic measurements of the left ventricle. Left ventricular mass index (LVMI) was calculated as left ventricular mass/height2.7. LVH by adult criteria was defined as LVMI > 51 g/m2.7 and by pediatric criteria as LVMI > 38.6 g/m2.7. Left ventricle geometry was classified as concentric, concentric remodeling, eccentric, or normal. Results. Data on 129 patients with a mean age of 13.6 ± 3.6 years were analyzed. The population was 67% male, 46.5% white, 38.0% African American, and 15.5% Hispanic. The prevalence of LVH was 15.5% using adult criteria and 41.1% using pediatric criteria. Increasing body mass index (BMI) was associated with a higher LVMI. Using either pediatric or adult criteria LVH was associated with BMI ≥95th percentile for age and gender. LVH and concentric hypertrophy were identified most frequently in Hispanic children. Conclusions. LVH occurs commonly in children with hypertension and is associated with an increased BMI. LVH may be more prevalent in Hispanic children than in other ethnic groups. Prevention and treatment of obesity is important in reducing the cardiovascular risk for children with hypertension. Further evaluation of the frequency of LVH in multiethnic populations is needed.

AB - Objective. To determine the prevalence of left ventricular hypertrophy (LVH) in a multiethnic group of children and adolescents with hypertension. Design/Methods. Pooled data from 1998 to 2001 from 3 sites belonging to the International Pediatric Hypertension Association were reviewed. Patients undergoing echocardiography to detect LVH as part of the evaluation for hypertension were included for analysis. Left ventricular mass was calculated from 2-dimensional guided M-mode echocardiographic measurements of the left ventricle. Left ventricular mass index (LVMI) was calculated as left ventricular mass/height2.7. LVH by adult criteria was defined as LVMI > 51 g/m2.7 and by pediatric criteria as LVMI > 38.6 g/m2.7. Left ventricle geometry was classified as concentric, concentric remodeling, eccentric, or normal. Results. Data on 129 patients with a mean age of 13.6 ± 3.6 years were analyzed. The population was 67% male, 46.5% white, 38.0% African American, and 15.5% Hispanic. The prevalence of LVH was 15.5% using adult criteria and 41.1% using pediatric criteria. Increasing body mass index (BMI) was associated with a higher LVMI. Using either pediatric or adult criteria LVH was associated with BMI ≥95th percentile for age and gender. LVH and concentric hypertrophy were identified most frequently in Hispanic children. Conclusions. LVH occurs commonly in children with hypertension and is associated with an increased BMI. LVH may be more prevalent in Hispanic children than in other ethnic groups. Prevention and treatment of obesity is important in reducing the cardiovascular risk for children with hypertension. Further evaluation of the frequency of LVH in multiethnic populations is needed.

KW - Children

KW - Echocardiography

KW - Hypertension

KW - Left ventricular hypertrophy

KW - Obesity

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