The effects of outward forced convective flow on inward diffusion in human dentine in vitro

D. H. Pashley; W. G. Matthews

doi:10.1016/0003-9969(93)90122-3

The effects of outward forced convective flow on inward diffusion in human dentine in vitro

D. H. Pashley, W. G. Matthews

Research output: Contribution to journal › Article › peer-review

60 Scopus citations

Abstract

In vitro experiments were conducted to evaluate the influence of outward forced convective flow on the inward diffusion of radioactive iodide. When the smear layer was present, application of 15cmH₂O (1.47kPa) outward-directed filtration pressure reduced the inward flux of iodide by about 10-20% depending upon the hydraulic conductance of each specimen. When the smear layer was removed by acid etching, the same 1.47 kPa pressure lowered the inward iodide flux by as much as 60%, depending on the hydraulic conductance. The results demonstrate the importance of the balance between inward diffusion and outward bulk-fluid movement on the rate of permeation of exogenous solutes.

Original language	English (US)
Pages (from-to)	577-582
Number of pages	6
Journal	Archives of Oral Biology
Volume	38
Issue number	7
DOIs	https://doi.org/10.1016/0003-9969(93)90122-3
State	Published - Jul 1993
Externally published	Yes

Keywords

dentine fluid flow
diffusion
pulpal pressure
smear layer

ASJC Scopus subject areas

Otorhinolaryngology
Dentistry(all)
Cell Biology

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10.1016/0003-9969(93)90122-3

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title = "The effects of outward forced convective flow on inward diffusion in human dentine in vitro",

abstract = "In vitro experiments were conducted to evaluate the influence of outward forced convective flow on the inward diffusion of radioactive iodide. When the smear layer was present, application of 15cmH2O (1.47kPa) outward-directed filtration pressure reduced the inward flux of iodide by about 10-20% depending upon the hydraulic conductance of each specimen. When the smear layer was removed by acid etching, the same 1.47 kPa pressure lowered the inward iodide flux by as much as 60%, depending on the hydraulic conductance. The results demonstrate the importance of the balance between inward diffusion and outward bulk-fluid movement on the rate of permeation of exogenous solutes.",

keywords = "dentine fluid flow, diffusion, pulpal pressure, smear layer",

author = "Pashley, {D. H.} and Matthews, {W. G.}",

note = "Funding Information: Acknowledgemenfs-We are grateful to Dr Keith Krell for suggesting the use of indexing pins for disc orientation. Dr Bruce Matthews originally hypothesized that the inward flux of substance may be greater in the presence of a smear layer than in its absence;o ur discussions with him were very helpful. We especially acknowledge the critical review of the data by Dr Athanasios G. Konstandopoulos for a number of helpful suggestions. We are grateful to Shirley Johnston for secretarial support. This work was supported, in part. by Grant DE06427 from the National Institute of Dental Research and by the Medical College of Georgia Dental Research Center.",

year = "1993",

month = jul,

doi = "10.1016/0003-9969(93)90122-3",

language = "English (US)",

volume = "38",

pages = "577--582",

journal = "Archives of Oral Biology",

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AU - Pashley, D. H.

AU - Matthews, W. G.

N1 - Funding Information: Acknowledgemenfs-We are grateful to Dr Keith Krell for suggesting the use of indexing pins for disc orientation. Dr Bruce Matthews originally hypothesized that the inward flux of substance may be greater in the presence of a smear layer than in its absence;o ur discussions with him were very helpful. We especially acknowledge the critical review of the data by Dr Athanasios G. Konstandopoulos for a number of helpful suggestions. We are grateful to Shirley Johnston for secretarial support. This work was supported, in part. by Grant DE06427 from the National Institute of Dental Research and by the Medical College of Georgia Dental Research Center.

PY - 1993/7

Y1 - 1993/7

N2 - In vitro experiments were conducted to evaluate the influence of outward forced convective flow on the inward diffusion of radioactive iodide. When the smear layer was present, application of 15cmH2O (1.47kPa) outward-directed filtration pressure reduced the inward flux of iodide by about 10-20% depending upon the hydraulic conductance of each specimen. When the smear layer was removed by acid etching, the same 1.47 kPa pressure lowered the inward iodide flux by as much as 60%, depending on the hydraulic conductance. The results demonstrate the importance of the balance between inward diffusion and outward bulk-fluid movement on the rate of permeation of exogenous solutes.

AB - In vitro experiments were conducted to evaluate the influence of outward forced convective flow on the inward diffusion of radioactive iodide. When the smear layer was present, application of 15cmH2O (1.47kPa) outward-directed filtration pressure reduced the inward flux of iodide by about 10-20% depending upon the hydraulic conductance of each specimen. When the smear layer was removed by acid etching, the same 1.47 kPa pressure lowered the inward iodide flux by as much as 60%, depending on the hydraulic conductance. The results demonstrate the importance of the balance between inward diffusion and outward bulk-fluid movement on the rate of permeation of exogenous solutes.

KW - dentine fluid flow

KW - diffusion

KW - pulpal pressure

KW - smear layer

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EP - 582

JO - Archives of Oral Biology

JF - Archives of Oral Biology

IS - 7

ER -

The effects of outward forced convective flow on inward diffusion in human dentine in vitro

Abstract

Keywords

ASJC Scopus subject areas

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