The effects of Pain-Free® desensitizer on dentine permeability and tubule occlusion over time, in vitro

Y. Zhang, K. Agee, D. H. Pashley, E. L. Pashley

Research output: Contribution to journalArticle

29 Scopus citations

Abstract

The purpose of this in vitro study was to evaluate the efficacy of a new resin emulsion (Pain-Free® Desensitizer) treatment for dentine hypersensitivity, for its ability to decrease dentine permeability. Crown segments were prepared from extracted, unerupted human 3rd molars by horizontal sectioning to remove occlusal enamel and the roots. The specimens were allocated in one of two groups: In group 1, the dentine surface was acid-etched to simulate the patent tubules of hypersensitive dentine. In group 2, the mineralized dentine surface was polished free of smear layer using a hydroxyapatite paste and ultrasonication. The hydraulic conductance of each specimen was then measured to obtain a pretreatment of control value. After a single treatment with resin desensitizer, the permeability was remeasured at 5 min, 1 day, 1 week and 1 month. Between measurements, the specimens were stored in buffer solution to simulate the solubilizing effects of saliva. Parallel specimens were followed by SEM examination. The results showed that a single treatment with resin desensitizer produced large, immediate, reductions in dentine permeability in both acid-etched and mineralized surfaces. In the acid-etched (group 1) specimens, the permeability returned to control values within 7 days, while the permeability of the group 2 specimens remained low even after 30 days of soaking. This simple treatment for occluding dentinal tubules may provide sufficient temporary reduction in dentine permeability to permit the development of natural desensitization.

Original languageEnglish (US)
Pages (from-to)884-891
Number of pages8
JournalJournal of Clinical Periodontology
Volume25
Issue number11 PART I
DOIs
StatePublished - Jan 1 1998

Keywords

  • Dentine
  • Dentine hypersensitivity
  • Desensitizer
  • Permeability

ASJC Scopus subject areas

  • Periodontics

Fingerprint Dive into the research topics of 'The effects of Pain-Free® desensitizer on dentine permeability and tubule occlusion over time, in vitro'. Together they form a unique fingerprint.

  • Cite this