The effects of restraint stress on intake of preferred and nonpreferred solutions in rodents

Leigh Anne Howell, Ruth Babette Harris, Crystal Clarke, Bradley D. Youngblood, Donna H. Ryan, Timothy A. Gilbertson

Research output: Contribution to journalArticle

10 Citations (Scopus)

Abstract

In these experiments we determined whether stress influenced intake of different flavored test solutions or only those that were preferred. In a series of studies, rats or hamsters were exposed to acute (1 h) or repeated (3 h/day for 3 days) restraint stress immediately followed by access to one of four tastants (saccharin, salt, citric acid, or quinine solutions) paired with water in a 24-h preference test. As rats prefer salt and hamsters do not, both species were used to test the effects of stress on preferred vs. nonpreferred solutions using the same stimulus. Acute restraint inhibited intake of saccharin in rats but had no effect on preference, indicating that suppression of intake was not due to changes in hedonic response. Restraint had no effect on saccharin intake of hamsters but significantly increased salt intake. However, as the preference ratio remained low for the solution (0.26), the stress-induced increase in salt intake was probably associated with a disturbance of sodium and fluid balance rather than a change in sensory perception. This was supported by stress having no effect on intake of nonpreferred solutions in rats or hamsters. Repeated restraint had no effect on salt or saccharin intake of rats when test solutions were presented after stress, but rats showed no preference for saccharin in a subsequent study in which the solution was associated with onset of stress. These results indicate that stress has specific effects on saccharin and salt intake that are not limited to preferred solutions.

Original languageEnglish (US)
Pages (from-to)697-704
Number of pages8
JournalPhysiology and Behavior
Volume65
Issue number4-5
DOIs
StatePublished - Jan 1 1998
Externally publishedYes

Fingerprint

Saccharin
Rodentia
Salts
Cricetinae
Pleasure
Water-Electrolyte Balance
Quinine
Exercise Test
Citric Acid
Sodium
Water

Keywords

  • Hamsters
  • Ingestive behavior
  • Rats
  • Restraint stress
  • Taste preference

ASJC Scopus subject areas

  • Experimental and Cognitive Psychology
  • Behavioral Neuroscience

Cite this

The effects of restraint stress on intake of preferred and nonpreferred solutions in rodents. / Howell, Leigh Anne; Harris, Ruth Babette; Clarke, Crystal; Youngblood, Bradley D.; Ryan, Donna H.; Gilbertson, Timothy A.

In: Physiology and Behavior, Vol. 65, No. 4-5, 01.01.1998, p. 697-704.

Research output: Contribution to journalArticle

Howell, Leigh Anne ; Harris, Ruth Babette ; Clarke, Crystal ; Youngblood, Bradley D. ; Ryan, Donna H. ; Gilbertson, Timothy A. / The effects of restraint stress on intake of preferred and nonpreferred solutions in rodents. In: Physiology and Behavior. 1998 ; Vol. 65, No. 4-5. pp. 697-704.
@article{44683eeaba2d4e1fbceb99e040386220,
title = "The effects of restraint stress on intake of preferred and nonpreferred solutions in rodents",
abstract = "In these experiments we determined whether stress influenced intake of different flavored test solutions or only those that were preferred. In a series of studies, rats or hamsters were exposed to acute (1 h) or repeated (3 h/day for 3 days) restraint stress immediately followed by access to one of four tastants (saccharin, salt, citric acid, or quinine solutions) paired with water in a 24-h preference test. As rats prefer salt and hamsters do not, both species were used to test the effects of stress on preferred vs. nonpreferred solutions using the same stimulus. Acute restraint inhibited intake of saccharin in rats but had no effect on preference, indicating that suppression of intake was not due to changes in hedonic response. Restraint had no effect on saccharin intake of hamsters but significantly increased salt intake. However, as the preference ratio remained low for the solution (0.26), the stress-induced increase in salt intake was probably associated with a disturbance of sodium and fluid balance rather than a change in sensory perception. This was supported by stress having no effect on intake of nonpreferred solutions in rats or hamsters. Repeated restraint had no effect on salt or saccharin intake of rats when test solutions were presented after stress, but rats showed no preference for saccharin in a subsequent study in which the solution was associated with onset of stress. These results indicate that stress has specific effects on saccharin and salt intake that are not limited to preferred solutions.",
keywords = "Hamsters, Ingestive behavior, Rats, Restraint stress, Taste preference",
author = "Howell, {Leigh Anne} and Harris, {Ruth Babette} and Crystal Clarke and Youngblood, {Bradley D.} and Ryan, {Donna H.} and Gilbertson, {Timothy A.}",
year = "1998",
month = "1",
day = "1",
doi = "10.1016/S0031-9384(98)00223-6",
language = "English (US)",
volume = "65",
pages = "697--704",
journal = "Physiology and Behavior",
issn = "0031-9384",
publisher = "Elsevier Inc.",
number = "4-5",

}

TY - JOUR

T1 - The effects of restraint stress on intake of preferred and nonpreferred solutions in rodents

AU - Howell, Leigh Anne

AU - Harris, Ruth Babette

AU - Clarke, Crystal

AU - Youngblood, Bradley D.

AU - Ryan, Donna H.

AU - Gilbertson, Timothy A.

PY - 1998/1/1

Y1 - 1998/1/1

N2 - In these experiments we determined whether stress influenced intake of different flavored test solutions or only those that were preferred. In a series of studies, rats or hamsters were exposed to acute (1 h) or repeated (3 h/day for 3 days) restraint stress immediately followed by access to one of four tastants (saccharin, salt, citric acid, or quinine solutions) paired with water in a 24-h preference test. As rats prefer salt and hamsters do not, both species were used to test the effects of stress on preferred vs. nonpreferred solutions using the same stimulus. Acute restraint inhibited intake of saccharin in rats but had no effect on preference, indicating that suppression of intake was not due to changes in hedonic response. Restraint had no effect on saccharin intake of hamsters but significantly increased salt intake. However, as the preference ratio remained low for the solution (0.26), the stress-induced increase in salt intake was probably associated with a disturbance of sodium and fluid balance rather than a change in sensory perception. This was supported by stress having no effect on intake of nonpreferred solutions in rats or hamsters. Repeated restraint had no effect on salt or saccharin intake of rats when test solutions were presented after stress, but rats showed no preference for saccharin in a subsequent study in which the solution was associated with onset of stress. These results indicate that stress has specific effects on saccharin and salt intake that are not limited to preferred solutions.

AB - In these experiments we determined whether stress influenced intake of different flavored test solutions or only those that were preferred. In a series of studies, rats or hamsters were exposed to acute (1 h) or repeated (3 h/day for 3 days) restraint stress immediately followed by access to one of four tastants (saccharin, salt, citric acid, or quinine solutions) paired with water in a 24-h preference test. As rats prefer salt and hamsters do not, both species were used to test the effects of stress on preferred vs. nonpreferred solutions using the same stimulus. Acute restraint inhibited intake of saccharin in rats but had no effect on preference, indicating that suppression of intake was not due to changes in hedonic response. Restraint had no effect on saccharin intake of hamsters but significantly increased salt intake. However, as the preference ratio remained low for the solution (0.26), the stress-induced increase in salt intake was probably associated with a disturbance of sodium and fluid balance rather than a change in sensory perception. This was supported by stress having no effect on intake of nonpreferred solutions in rats or hamsters. Repeated restraint had no effect on salt or saccharin intake of rats when test solutions were presented after stress, but rats showed no preference for saccharin in a subsequent study in which the solution was associated with onset of stress. These results indicate that stress has specific effects on saccharin and salt intake that are not limited to preferred solutions.

KW - Hamsters

KW - Ingestive behavior

KW - Rats

KW - Restraint stress

KW - Taste preference

UR - http://www.scopus.com/inward/record.url?scp=0032464897&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0032464897&partnerID=8YFLogxK

U2 - 10.1016/S0031-9384(98)00223-6

DO - 10.1016/S0031-9384(98)00223-6

M3 - Article

C2 - 10073470

AN - SCOPUS:0032464897

VL - 65

SP - 697

EP - 704

JO - Physiology and Behavior

JF - Physiology and Behavior

SN - 0031-9384

IS - 4-5

ER -