The effects of smoking on short-term quality of life outcomes in sinus surgery

Subinoy Das, Adam M. Becker, Helen Perakis, John Drew Prosser, Stilianos E Kountakis

Research output: Contribution to journalArticle

18 Citations (Scopus)

Abstract

OBJECTIVE: The purpose of this study was to prospectively compare the short-term benefit of endoscopic sinus surgery for smokers and nonsmokers using a disease specific, clinically validated, quality of life outcomes measure, the Sinonasal Outcomes Test-20 (SNOT-20). STUDY DESIGN: Prospective clinical trial. METHODS: A total of 235 patients were prospectively enrolled at a single tertiary academic center. Preoperative SNOT-20 scores and comprehensive demographic data were obtained. All patients underwent endoscopic sinus surgery under the supervision of the senior author. Preoperative SNOT-20 scores were compared to short-term postoperative SNOT-20 scores. RESULTS: Short-term postoperative results were available for 221 patients for comparison. Preoperative SNOT-20 scores in 49 smokers (mean: 27.8) and 172 nonsmokers (mean: 26.2) were statistically similar. Both smokers and nonsmokers achieved a highly significant reduction in SNOT-20 scores at short-term follow-up evaluations. (P < .0005) Smokers achieved a greater reduction in SNOT-20 scores (mean difference: 22.1) at short-term follow-up compared to nonsmokers (mean difference: 16.1). This result was statistically significant (P < .044). CONCLUSIONS: This study confirms that smokers and nonsmokers achieve a highly significant short-term benefit from endoscopic sinus surgery using a clinically-validated symptom severity scale in a prospective study. Interestingly, smokers achieved a greater short-term benefit than nonsmokers did. This study calls into question the notion that current smokers are poorer candidates for endoscopic sinus surgery. Further prospective studies to confirm these results and provide long-term analysis should be performed.

Original languageEnglish (US)
Pages (from-to)2229-2232
Number of pages4
JournalLaryngoscope
Volume117
Issue number12
DOIs
StatePublished - Dec 1 2007

Fingerprint

Smoking
Quality of Life
Prospective Studies
Demography
Outcome Assessment (Health Care)
Clinical Trials

Keywords

  • Endoscopic sinus surgery
  • Quality of life
  • SNOT-20
  • Smoking
  • Surgical outcomes

ASJC Scopus subject areas

  • Otorhinolaryngology

Cite this

The effects of smoking on short-term quality of life outcomes in sinus surgery. / Das, Subinoy; Becker, Adam M.; Perakis, Helen; Prosser, John Drew; Kountakis, Stilianos E.

In: Laryngoscope, Vol. 117, No. 12, 01.12.2007, p. 2229-2232.

Research output: Contribution to journalArticle

Das, Subinoy ; Becker, Adam M. ; Perakis, Helen ; Prosser, John Drew ; Kountakis, Stilianos E. / The effects of smoking on short-term quality of life outcomes in sinus surgery. In: Laryngoscope. 2007 ; Vol. 117, No. 12. pp. 2229-2232.
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AB - OBJECTIVE: The purpose of this study was to prospectively compare the short-term benefit of endoscopic sinus surgery for smokers and nonsmokers using a disease specific, clinically validated, quality of life outcomes measure, the Sinonasal Outcomes Test-20 (SNOT-20). STUDY DESIGN: Prospective clinical trial. METHODS: A total of 235 patients were prospectively enrolled at a single tertiary academic center. Preoperative SNOT-20 scores and comprehensive demographic data were obtained. All patients underwent endoscopic sinus surgery under the supervision of the senior author. Preoperative SNOT-20 scores were compared to short-term postoperative SNOT-20 scores. RESULTS: Short-term postoperative results were available for 221 patients for comparison. Preoperative SNOT-20 scores in 49 smokers (mean: 27.8) and 172 nonsmokers (mean: 26.2) were statistically similar. Both smokers and nonsmokers achieved a highly significant reduction in SNOT-20 scores at short-term follow-up evaluations. (P < .0005) Smokers achieved a greater reduction in SNOT-20 scores (mean difference: 22.1) at short-term follow-up compared to nonsmokers (mean difference: 16.1). This result was statistically significant (P < .044). CONCLUSIONS: This study confirms that smokers and nonsmokers achieve a highly significant short-term benefit from endoscopic sinus surgery using a clinically-validated symptom severity scale in a prospective study. Interestingly, smokers achieved a greater short-term benefit than nonsmokers did. This study calls into question the notion that current smokers are poorer candidates for endoscopic sinus surgery. Further prospective studies to confirm these results and provide long-term analysis should be performed.

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