The immune response of the mouse to lymphocytic choriomeningitis virus. III. Differences of numbers of cytotoxic T lymphocytes in spleens of mice of different strains

Demetrius Moskophidis, Fritz Lehmann-Grube

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Abstract

By use of an accurate procedure for the measurement of relative numbers of murine cytotoxic T lymphocytes (CTL) marked differences of lymphocytic Choriomeningitis virus-specific CTL in spleens were found among mouse strains that ranged from low over intermediate and high to very high, suggesting a gradient of responses rather than distinct classes. Differences were also found between mice sharing the major histocompatibility complex.

Original languageEnglish (US)
Pages (from-to)279-289
Number of pages11
JournalCellular Immunology
Volume77
Issue number2
DOIs
StatePublished - Apr 15 1983

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Lymphocytic choriomeningitis virus
Cytotoxic T-Lymphocytes
Spleen
Major Histocompatibility Complex

ASJC Scopus subject areas

  • Immunology

Cite this

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