The influence of bio-behavioural factors on tumour biology: Pathways and mechanisms

Michael H. Antoni, Susan K. Lutgendorf, Steven W. Cole, Firdaus S. Dhabhar, Sandra E. Sephton, Paige Green McDonald, Michael Edward Stefanek, Anil K. Sood

Research output: Contribution to journalReview article

578 Citations (Scopus)

Abstract

Epidemiological studies indicate that stress, chronic depression and lack of social support might serve as risk factors for cancer development and progression. Recent cellular and molecular studies have identified biological processes that could potentially mediate such effects. This review integrates clinical, cellular and molecular studies to provide a mechanistic understanding of the interface between biological and behavioural influences in cancer, and identifies novel behavioural or pharmacological interventions that might help improve cancer outcomes.

Original languageEnglish (US)
Pages (from-to)240-248
Number of pages9
JournalNature Reviews Cancer
Volume6
Issue number3
DOIs
StatePublished - Mar 1 2006
Externally publishedYes

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Biological Phenomena
Neoplasms
Social Support
Epidemiologic Studies
Pharmacology

ASJC Scopus subject areas

  • Oncology
  • Cancer Research

Cite this

Antoni, M. H., Lutgendorf, S. K., Cole, S. W., Dhabhar, F. S., Sephton, S. E., McDonald, P. G., ... Sood, A. K. (2006). The influence of bio-behavioural factors on tumour biology: Pathways and mechanisms. Nature Reviews Cancer, 6(3), 240-248. https://doi.org/10.1038/nrc1820

The influence of bio-behavioural factors on tumour biology : Pathways and mechanisms. / Antoni, Michael H.; Lutgendorf, Susan K.; Cole, Steven W.; Dhabhar, Firdaus S.; Sephton, Sandra E.; McDonald, Paige Green; Stefanek, Michael Edward; Sood, Anil K.

In: Nature Reviews Cancer, Vol. 6, No. 3, 01.03.2006, p. 240-248.

Research output: Contribution to journalReview article

Antoni, MH, Lutgendorf, SK, Cole, SW, Dhabhar, FS, Sephton, SE, McDonald, PG, Stefanek, ME & Sood, AK 2006, 'The influence of bio-behavioural factors on tumour biology: Pathways and mechanisms', Nature Reviews Cancer, vol. 6, no. 3, pp. 240-248. https://doi.org/10.1038/nrc1820
Antoni MH, Lutgendorf SK, Cole SW, Dhabhar FS, Sephton SE, McDonald PG et al. The influence of bio-behavioural factors on tumour biology: Pathways and mechanisms. Nature Reviews Cancer. 2006 Mar 1;6(3):240-248. https://doi.org/10.1038/nrc1820
Antoni, Michael H. ; Lutgendorf, Susan K. ; Cole, Steven W. ; Dhabhar, Firdaus S. ; Sephton, Sandra E. ; McDonald, Paige Green ; Stefanek, Michael Edward ; Sood, Anil K. / The influence of bio-behavioural factors on tumour biology : Pathways and mechanisms. In: Nature Reviews Cancer. 2006 ; Vol. 6, No. 3. pp. 240-248.
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