The influence of BMI on the association between serum lycopene and the metabolic syndrome

Guang Ming Han, Ghada A. Soliman, Jane L. Meza, Km Islam, Shinobu Watanabe-Galloway

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

Overweight and obese individuals have an increased risk of developing the metabolic syndrome because of subsequent chronic inflammation and oxidative stress, which the antioxidant nutrient lycopene can reduce. However, studies indicate that different BMI statuses can alter the positive effects of lycopene. Therefore, the purpose of this study was to examine how BMI influences the association between serum lycopene and the metabolic syndrome. The tertile rank method was used to divide 13 196 participants, aged 20 years and older, into three groups according to serum concentrations of lycopene. The associations between serum lycopene and the metabolic syndrome were analysed separately for normal-weight, overweight and obese participants. Overall, the prevalence of the metabolic syndrome was significantly higher in the first tertile group (OR 38·6 %; 95 % CI 36·9, 40·3) compared with the second tertile group (OR 29·3 %; 95 % CI 27·5, 31·1) and the third tertile group (OR 26·6 %; 95 % CI 24·9, 28·3). However, the associations between lycopene and the metabolic syndrome were only significant for normal-weight and overweight participants (P<0·05), but not for obese participants (P>0·05), even after adjusting for possible confounding variables. In conclusion, BMI appears to strongly influence the association between serum lycopene and the metabolic syndrome.

Original languageEnglish (US)
Pages (from-to)1292-1300
Number of pages9
JournalBritish Journal of Nutrition
Volume115
Issue number7
DOIs
StatePublished - Feb 11 2016

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Serum
Weights and Measures
Confounding Factors (Epidemiology)
lycopene
Oxidative Stress
Antioxidants
Inflammation
Food

Keywords

  • Antioxidant
  • Carotenoids
  • Obesity
  • Overweight
  • Oxidative stress
  • Physical activity

ASJC Scopus subject areas

  • Medicine (miscellaneous)
  • Nutrition and Dietetics

Cite this

The influence of BMI on the association between serum lycopene and the metabolic syndrome. / Han, Guang Ming; Soliman, Ghada A.; Meza, Jane L.; Islam, Km; Watanabe-Galloway, Shinobu.

In: British Journal of Nutrition, Vol. 115, No. 7, 11.02.2016, p. 1292-1300.

Research output: Contribution to journalArticle

Han, Guang Ming ; Soliman, Ghada A. ; Meza, Jane L. ; Islam, Km ; Watanabe-Galloway, Shinobu. / The influence of BMI on the association between serum lycopene and the metabolic syndrome. In: British Journal of Nutrition. 2016 ; Vol. 115, No. 7. pp. 1292-1300.
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