The influence of dentin permeability and pulpal blood flow on pulpal solute concentrations

David H. Pashley

Research output: Contribution to journalArticlepeer-review

57 Scopus citations

Abstract

The rate of permeation of substances through dentin depends on the molecular size, the surface area available for diffusion, the patency of dentinal tubules, and the thickness of the remaining dentin. Topically applied substances as large as albumin readily permeate dentin and are absorbed into the systemic circulation. The pulpal concentration of substances diffusing across dentin depends on both the rate of permeation and the rate of removal via the pulpal circulation.

Original languageEnglish (US)
Pages (from-to)355-361
Number of pages7
JournalJournal of endodontics
Volume5
Issue number12
DOIs
StatePublished - Dec 1979
Externally publishedYes

ASJC Scopus subject areas

  • General Dentistry

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