The influence of dentin permeability and pulpal blood flow on pulpal solute concentrations

David Henry Pashley

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The rate of permeation of substances through dentin depends on the molecular size, the surface area available for diffusion, the patency of dentinal tubules, and the thickness of the remaining dentin. Topically applied substances as large as albumin readily permeate dentin and are absorbed into the systemic circulation. The pulpal concentration of substances diffusing across dentin depends on both the rate of permeation and the rate of removal via the pulpal circulation.

Original languageEnglish (US)
Pages (from-to)355-361
Number of pages7
JournalJournal of Endodontics
Issue number12
Publication statusPublished - Jan 1 1979


ASJC Scopus subject areas

  • Dentistry(all)

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