The prostate of the nonhuman primate: Normal anatomy and pathology

Ronald W Lewis, J. C.S. Kim, D. Irani, J. A. Roberts

Research output: Contribution to journalArticle

35 Citations (Scopus)

Abstract

The caudal and cranial prostate of different species of nonhuman primates were examined for histologic characteristics and pathological abnormalities. One hundred specimens from 12 species were represented. Among the pathologies found were: 1) cystic hyperplasia; 2) fibromuscular hyperplasia; 3) squamous metaplasia; 4) chronic and acute bacterial prostatitis; 5) prostate adenocarcinoma; and 6) other miscellaneous pathologic changes. A historical review of histological characteristics and pathological abnormalities of the nonhuman primate prostate is given. Based upon findings in this study, anatomical similarity of the caudal lobe of the prostate to the peripheral zone of the prostate in humans as described by McNeal is found. In the patas monkey the relationship of the cranial and caudal lobe suggests strongly the relationship seen between the central and peripheral zones in man. The case of prostatic adenocarcinoma described has only been reported in one other nonhuman primate.

Original languageEnglish (US)
Pages (from-to)51-70
Number of pages20
JournalThe Prostate
Volume2
Issue number1
DOIs
StatePublished - Jan 1 1981

Fingerprint

Primates
Prostate
Anatomy
Pathology
Prostatitis
Hyperplasia
Adenocarcinoma
Erythrocebus patas
Metaplasia

Keywords

  • adenocarcinoma
  • benign cystic hyperplasia
  • comparative anatomy
  • nonhuman primate

ASJC Scopus subject areas

  • Oncology
  • Urology

Cite this

Lewis, R. W., Kim, J. C. S., Irani, D., & Roberts, J. A. (1981). The prostate of the nonhuman primate: Normal anatomy and pathology. The Prostate, 2(1), 51-70. https://doi.org/10.1002/pros.2990020106

The prostate of the nonhuman primate : Normal anatomy and pathology. / Lewis, Ronald W; Kim, J. C.S.; Irani, D.; Roberts, J. A.

In: The Prostate, Vol. 2, No. 1, 01.01.1981, p. 51-70.

Research output: Contribution to journalArticle

Lewis, RW, Kim, JCS, Irani, D & Roberts, JA 1981, 'The prostate of the nonhuman primate: Normal anatomy and pathology', The Prostate, vol. 2, no. 1, pp. 51-70. https://doi.org/10.1002/pros.2990020106
Lewis, Ronald W ; Kim, J. C.S. ; Irani, D. ; Roberts, J. A. / The prostate of the nonhuman primate : Normal anatomy and pathology. In: The Prostate. 1981 ; Vol. 2, No. 1. pp. 51-70.
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