The regulation and function of micrornas in kidney diseases

QingQing Wei, Qing Sheng Mi, Zheng Dong

Research output: Contribution to journalReview article

54 Citations (Scopus)

Abstract

MicroRNAs (miRNA) are endogenous short noncoding RNAs, which regulate virtually all major cellular processes by inhibiting target gene expression. In kidneys, miRNAs have been implicated in renal development, homeostasis, and physiological functions. In addition, miRNAs play important roles in the pathogenesis of various renal diseases, including renal carcinoma, diabetic nephropathy, acute kidney injury, hypertensive nephropathy, polycystic kidney disease, and others. Furthermore, miRNAs may have great values as biomarkers in different kidney diseases.

Original languageEnglish (US)
Pages (from-to)602-615
Number of pages14
JournalIUBMB Life
Volume65
Issue number7
DOIs
StatePublished - Jul 1 2013

Fingerprint

Kidney Diseases
MicroRNAs
Kidney
Small Untranslated RNA
Polycystic Kidney Diseases
Diabetic Nephropathies
Biomarkers
Acute Kidney Injury
Gene expression
Homeostasis
Carcinoma
Gene Expression

Keywords

  • acute kidney injury
  • allograft rejection
  • biomarkers
  • chronic kidney disease
  • diabetic nephropathy
  • hypertensive nephropathy
  • kidney
  • microRNA
  • polycystic kidney disease
  • renal cell carcinoma

ASJC Scopus subject areas

  • Biochemistry
  • Molecular Biology
  • Genetics
  • Clinical Biochemistry
  • Cell Biology

Cite this

The regulation and function of micrornas in kidney diseases. / Wei, QingQing; Mi, Qing Sheng; Dong, Zheng.

In: IUBMB Life, Vol. 65, No. 7, 01.07.2013, p. 602-615.

Research output: Contribution to journalReview article

Wei, QingQing ; Mi, Qing Sheng ; Dong, Zheng. / The regulation and function of micrornas in kidney diseases. In: IUBMB Life. 2013 ; Vol. 65, No. 7. pp. 602-615.
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