TY - JOUR
T1 - The role of brain single photon emission computed tomography in the diagnosis of primary progressive aphasia
AU - Mcdaniel, Keith D.
AU - Wagner, Mark T.
AU - Greenspan, Bennett S.
PY - 1991/12
Y1 - 1991/12
N2 - We present two cases of primary progressive aphasia studied with neuropsychologic measures, computed tomography or magnetic resonance imaging, and single-photon emission computed tomography with technetium Tc 99m-labeled hexamethyl-propyleneamine oxime. Clinical and neuropsychologic observations revealed a marked, progressive loss of language functions over time with relative preservation of nonlanguage cognitive functions in both patients. The brain single-photon emission computed tomographic scan revealed marked left frontal and minimal left temporal and parietal hypoperfusion in case 1 and marked left posterior frontal and minimal left temporal hypoperfusion in case 2. The value of brain single-photon emission computed tomography in distinguishing primary progressive aphasia from Alzheimer's disease is described.
AB - We present two cases of primary progressive aphasia studied with neuropsychologic measures, computed tomography or magnetic resonance imaging, and single-photon emission computed tomography with technetium Tc 99m-labeled hexamethyl-propyleneamine oxime. Clinical and neuropsychologic observations revealed a marked, progressive loss of language functions over time with relative preservation of nonlanguage cognitive functions in both patients. The brain single-photon emission computed tomographic scan revealed marked left frontal and minimal left temporal and parietal hypoperfusion in case 1 and marked left posterior frontal and minimal left temporal hypoperfusion in case 2. The value of brain single-photon emission computed tomography in distinguishing primary progressive aphasia from Alzheimer's disease is described.
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U2 - 10.1001/archneur.1991.00530240061021
DO - 10.1001/archneur.1991.00530240061021
M3 - Article
C2 - 1845029
AN - SCOPUS:0026337896
VL - 48
SP - 1257
EP - 1260
JO - Archives of Neurology
JF - Archives of Neurology
SN - 0003-9942
IS - 12
ER -