The role of brain single photon emission computed tomography in the diagnosis of primary progressive aphasia

Keith D. Mcdaniel; Mark T. Wagner; Bennett S. Greenspan

doi:10.1001/archneur.1991.00530240061021

The role of brain single photon emission computed tomography in the diagnosis of primary progressive aphasia

Keith D. Mcdaniel, Mark T. Wagner, Bennett S. Greenspan

Radiology and Imaging

Research output: Contribution to journal › Article

37 Scopus citations

Abstract

We present two cases of primary progressive aphasia studied with neuropsychologic measures, computed tomography or magnetic resonance imaging, and single-photon emission computed tomography with technetium Tc 99m-labeled hexamethyl-propyleneamine oxime. Clinical and neuropsychologic observations revealed a marked, progressive loss of language functions over time with relative preservation of nonlanguage cognitive functions in both patients. The brain single-photon emission computed tomographic scan revealed marked left frontal and minimal left temporal and parietal hypoperfusion in case 1 and marked left posterior frontal and minimal left temporal hypoperfusion in case 2. The value of brain single-photon emission computed tomography in distinguishing primary progressive aphasia from Alzheimer's disease is described.

Original language	English (US)
Pages (from-to)	1257-1260
Number of pages	4
Journal	Archives of Neurology
Volume	48
Issue number	12
DOIs	https://doi.org/10.1001/archneur.1991.00530240061021
State	Published - Dec 1991

ASJC Scopus subject areas

Arts and Humanities (miscellaneous)
Clinical Neurology

Access to Document

10.1001/archneur.1991.00530240061021

Fingerprint Dive into the research topics of 'The role of brain single photon emission computed tomography in the diagnosis of primary progressive aphasia'. Together they form a unique fingerprint.

Cite this

Mcdaniel, K. D., Wagner, M. T., & Greenspan, B. S. (1991). The role of brain single photon emission computed tomography in the diagnosis of primary progressive aphasia. Archives of Neurology, 48(12), 1257-1260. https://doi.org/10.1001/archneur.1991.00530240061021

@article{ee213a77e54b43dd97868383670bd48f,

title = "The role of brain single photon emission computed tomography in the diagnosis of primary progressive aphasia",

abstract = "We present two cases of primary progressive aphasia studied with neuropsychologic measures, computed tomography or magnetic resonance imaging, and single-photon emission computed tomography with technetium Tc 99m-labeled hexamethyl-propyleneamine oxime. Clinical and neuropsychologic observations revealed a marked, progressive loss of language functions over time with relative preservation of nonlanguage cognitive functions in both patients. The brain single-photon emission computed tomographic scan revealed marked left frontal and minimal left temporal and parietal hypoperfusion in case 1 and marked left posterior frontal and minimal left temporal hypoperfusion in case 2. The value of brain single-photon emission computed tomography in distinguishing primary progressive aphasia from Alzheimer's disease is described.",

author = "Mcdaniel, {Keith D.} and Wagner, {Mark T.} and Greenspan, {Bennett S.}",

year = "1991",

month = dec,

doi = "10.1001/archneur.1991.00530240061021",

language = "English (US)",

volume = "48",

pages = "1257--1260",

journal = "Archives of Neurology",

issn = "0003-9942",

publisher = "American Medical Association",

number = "12",

}

TY - JOUR

T1 - The role of brain single photon emission computed tomography in the diagnosis of primary progressive aphasia

AU - Mcdaniel, Keith D.

AU - Wagner, Mark T.

AU - Greenspan, Bennett S.

PY - 1991/12

Y1 - 1991/12

N2 - We present two cases of primary progressive aphasia studied with neuropsychologic measures, computed tomography or magnetic resonance imaging, and single-photon emission computed tomography with technetium Tc 99m-labeled hexamethyl-propyleneamine oxime. Clinical and neuropsychologic observations revealed a marked, progressive loss of language functions over time with relative preservation of nonlanguage cognitive functions in both patients. The brain single-photon emission computed tomographic scan revealed marked left frontal and minimal left temporal and parietal hypoperfusion in case 1 and marked left posterior frontal and minimal left temporal hypoperfusion in case 2. The value of brain single-photon emission computed tomography in distinguishing primary progressive aphasia from Alzheimer's disease is described.

AB - We present two cases of primary progressive aphasia studied with neuropsychologic measures, computed tomography or magnetic resonance imaging, and single-photon emission computed tomography with technetium Tc 99m-labeled hexamethyl-propyleneamine oxime. Clinical and neuropsychologic observations revealed a marked, progressive loss of language functions over time with relative preservation of nonlanguage cognitive functions in both patients. The brain single-photon emission computed tomographic scan revealed marked left frontal and minimal left temporal and parietal hypoperfusion in case 1 and marked left posterior frontal and minimal left temporal hypoperfusion in case 2. The value of brain single-photon emission computed tomography in distinguishing primary progressive aphasia from Alzheimer's disease is described.

UR - http://www.scopus.com/inward/record.url?scp=0026337896&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0026337896&partnerID=8YFLogxK

U2 - 10.1001/archneur.1991.00530240061021

DO - 10.1001/archneur.1991.00530240061021

M3 - Article

C2 - 1845029

AN - SCOPUS:0026337896

VL - 48

SP - 1257

EP - 1260

JO - Archives of Neurology

JF - Archives of Neurology

SN - 0003-9942

IS - 12

ER -