Abstract
We present two cases of primary progressive aphasia studied with neuropsychologic measures, computed tomography or magnetic resonance imaging, and single-photon emission computed tomography with technetium Tc 99m-labeled hexamethyl-propyleneamine oxime. Clinical and neuropsychologic observations revealed a marked, progressive loss of language functions over time with relative preservation of nonlanguage cognitive functions in both patients. The brain single-photon emission computed tomographic scan revealed marked left frontal and minimal left temporal and parietal hypoperfusion in case 1 and marked left posterior frontal and minimal left temporal hypoperfusion in case 2. The value of brain single-photon emission computed tomography in distinguishing primary progressive aphasia from Alzheimer's disease is described.
Original language | English (US) |
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Pages (from-to) | 1257-1260 |
Number of pages | 4 |
Journal | Archives of Neurology |
Volume | 48 |
Issue number | 12 |
DOIs | |
State | Published - Dec 1991 |
ASJC Scopus subject areas
- Arts and Humanities (miscellaneous)
- Clinical Neurology