Abstract
We present two cases of primary progressive aphasia studied with neuropsychologic measures, computed tomography or magnetic resonance imaging, and single-photon emission computed tomography with technetium Tc 99m-labeled hexamethyl-propyleneamine oxime. Clinical and neuropsychologic observations revealed a marked, progressive loss of language functions over time with relative preservation of nonlanguage cognitive functions in both patients. The brain single-photon emission computed tomographic scan revealed marked left frontal and minimal left temporal and parietal hypoperfusion in case 1 and marked left posterior frontal and minimal left temporal hypoperfusion in case 2. The value of brain single-photon emission computed tomography in distinguishing primary progressive aphasia from Alzheimer's disease is described.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 1257-1260 |
| Number of pages | 4 |
| Journal | Archives of Neurology |
| Volume | 48 |
| Issue number | 12 |
| DOIs | |
| State | Published - Dec 1991 |
ASJC Scopus subject areas
- Arts and Humanities (miscellaneous)
- Clinical Neurology