The role of brain single photon emission computed tomography in the diagnosis of primary progressive aphasia

Keith D. Mcdaniel, Mark T. Wagner, Bennett Steven Greenspan

Research output: Contribution to journalArticle

37 Citations (Scopus)

Abstract

We present two cases of primary progressive aphasia studied with neuropsychologic measures, computed tomography or magnetic resonance imaging, and single-photon emission computed tomography with technetium Tc 99m-labeled hexamethyl-propyleneamine oxime. Clinical and neuropsychologic observations revealed a marked, progressive loss of language functions over time with relative preservation of nonlanguage cognitive functions in both patients. The brain single-photon emission computed tomographic scan revealed marked left frontal and minimal left temporal and parietal hypoperfusion in case 1 and marked left posterior frontal and minimal left temporal hypoperfusion in case 2. The value of brain single-photon emission computed tomography in distinguishing primary progressive aphasia from Alzheimer's disease is described.

Original languageEnglish (US)
Pages (from-to)1257-1260
Number of pages4
JournalArchives of Neurology
Volume48
Issue number12
DOIs
StatePublished - Jan 1 1991

Fingerprint

Primary Progressive Aphasia
Single-Photon Emission-Computed Tomography
Brain
Oximes
Technetium
Photons
Cognition
Alzheimer Disease
Language
Tomography
Magnetic Resonance Imaging
Computed Tomography

ASJC Scopus subject areas

  • Arts and Humanities (miscellaneous)
  • Clinical Neurology

Cite this

The role of brain single photon emission computed tomography in the diagnosis of primary progressive aphasia. / Mcdaniel, Keith D.; Wagner, Mark T.; Greenspan, Bennett Steven.

In: Archives of Neurology, Vol. 48, No. 12, 01.01.1991, p. 1257-1260.

Research output: Contribution to journalArticle

Mcdaniel, Keith D. ; Wagner, Mark T. ; Greenspan, Bennett Steven. / The role of brain single photon emission computed tomography in the diagnosis of primary progressive aphasia. In: Archives of Neurology. 1991 ; Vol. 48, No. 12. pp. 1257-1260.
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