The significance of ictal depth EEG patterns in patients with temporal lobe epilepsy

Yong D. Park, Anthony M. Murro, Don W. King, Brian B. Gallagher, Joseph R. Smith, Farivar Yaghmai

Research output: Contribution to journalArticle

36 Scopus citations

Abstract

We reviewed 187 depth recorded seizures in 33 patients with non-lesional temporal lobe complex partial seizures. All patients had a minimum of 1 year follow-up following temporal lobectomy. We classified seizure onset pattern as rhythmic activity, attenuation, or repetitive spikes or spike wave complexes. The most common pattern of seizure onset was rhythmic activity and the next most common pattern was repetitive spikes. Seventy-five seizures (49%) had only one seizure onset pattern, and 79 seizures (51%) had a combination of seizure onset patterns. The degree of hippocampal gliosis strongly predicted the type of seizure onset pattern (Chi square = 24.07, 2 d.f., P < 0.01). The rhythmic activity pattern was associated with mild gliosis, and the repetitive spike pattern was associated with severe gliosis. We classified seizure onset as focal or regional based on the number of electrode contacts that were involved by the ictal EEG. A focal seizure onset was associated with an excellent outcome following temporal lobectomy.

Original languageEnglish (US)
Pages (from-to)412-415
Number of pages4
JournalElectroencephalography and Clinical Neurophysiology
Volume99
Issue number5
DOIs
StatePublished - Oct 1996

Keywords

  • Depth EEG
  • Epilepsy
  • Mesial temporal sclerosis
  • Outcome
  • Seizure morphology
  • Temporal lobe

ASJC Scopus subject areas

  • Neuroscience(all)
  • Clinical Neurology

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