Topography of skeletal muscle ryanodine receptors studied by atomic force microscopy

QingQing Wei, S. F. Chen, X. Y. Cheng, X. B. Yu, J. Hu, M. Q. Li, P. H. Zhu

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

Tapping mode atomic force microscopy is demonstrated for topographic investigation of isolated ryanodine receptors of rabbit skeletal muscle (RyR1) both in air and in a buffer. In air, the micrographs appeared to have four-fold symmetry and showed two different configurations depending on the presence or absence of a center protrusion. Despite the squareness of the images discerned of RyR1s in the buffer, the detailed topography of RyR1 appeared different from that in air. Possible reasons for this are discussed.

Original languageEnglish (US)
Pages (from-to)636-638
Number of pages3
JournalJournal of Vacuum Science and Technology B: Microelectronics and Nanometer Structures
Volume18
Issue number2
DOIs
StatePublished - Mar 1 2000
Externally publishedYes

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skeletal muscle
Topography
Muscle
Atomic force microscopy
topography
atomic force microscopy
air
buffers
Air
rabbits
symmetry
configurations

ASJC Scopus subject areas

  • Condensed Matter Physics
  • Electrical and Electronic Engineering

Cite this

Topography of skeletal muscle ryanodine receptors studied by atomic force microscopy. / Wei, QingQing; Chen, S. F.; Cheng, X. Y.; Yu, X. B.; Hu, J.; Li, M. Q.; Zhu, P. H.

In: Journal of Vacuum Science and Technology B: Microelectronics and Nanometer Structures, Vol. 18, No. 2, 01.03.2000, p. 636-638.

Research output: Contribution to journalArticle

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