Tourette syndrome associated with mental retardation: A single-subject treatment study with haloperidol

Peter B. Rosenquist, James W. Bodfish, Rebekah Thompson

Research output: Contribution to journalArticle

9 Scopus citations

Abstract

A Tic Checklist and direct observation tic measurement procedure were developed for the assessment of Tourette syndrome in individuals with mental retardation. Using a single-subject reversal design, we applied this assessment method to the evaluation of haloperidol treatment for a subject with Tourette syndrome and severe mental retardation. Relative to baseline, haloperidol 10 mg/day produced decreases of 66% in simple motor tics, 46% in complex motor tics, 45% in simple vocal tics, and 50% in complex vocal tics. Improvement was also seen in careprovider ratings of tic severity, hyperactivity, and compulsive behaviors.

Original languageEnglish (US)
Pages (from-to)497-504
Number of pages8
JournalAmerican Journal on Mental Retardation
Volume101
Issue number5
StatePublished - Mar 1 1997
Externally publishedYes

ASJC Scopus subject areas

  • Education
  • Rehabilitation
  • Developmental and Educational Psychology
  • Health Professions(all)

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