Traceless chemical ligation from S -, O -, and N-acyl isopeptides

Medicine & Life Sciences

• Ligation 100%
• Peptides 58%
• Cysteine 53%
• Cyclic Peptides 32%
• Protein Structural Elements 20%
• Solid-Phase Synthesis Techniques 18%
• Membrane Transport Proteins 13%
• Hydrogen Bonding 13%
• Return to Work 13%
• Amides 13%
• Microwaves 13%
• Hydrogen 13%
• Tryptophan 12%
• Amines 11%
• Serine 11%
• Buffers 10%
• Tyrosine 10%
• Polymers 10%
• Phosphates 9%
• Ions 9%
• Theoretical Models 9%
• Cell Membrane 8%
• Amino Acids 7%
• Enzymes 6%
• Pharmaceutical Preparations 4%
• Proteins 4%

Chemical Compounds

• Peptide 65%
• Cysteine 49%
• Transition State 34%
• Transacylation 21%
• Condensation 20%
• Cysteine Residue 14%
• Microwave Irradiation 13%
• Serine 13%
• Tryptophan 13%
• Tyrosine 12%
• Carbonyl Group 12%
• pH Value 11%
• Protein 11%
• Pharmaceutical 10%
• Amide 10%
• Phosphate 9%
• Buffer Solution 9%
• Amine 9%
• Reaction Yield 5%
• Ion 5%
• Acid 4%
• Molecule 4%