Traditional uses, phytochemistry and pharmacology of Clerodendron glandulosum Coleb – a review

Ravirajsinh N. Jadeja, Menaka C. Thounaojam, Thouchom Brojendro Singh, Ranjitsinh V. Devkar, A. V. Ramachandran

Research output: Contribution to journalArticle

9 Scopus citations

Abstract

Present review for the first time provides a complete botanical description and information on ethnomedicinal uses of Clerodendron glandulosum.Coleb (CG; Fam, Verbenaceae). Recent studies conducted from our laboratory provide pharmacological evidence for its anti-hypertensive, anti-diabetic and anti-obesity potentials. Further, its beneficial potential in preventing in vitro and in vivo non-alcoholic steatohepatitis and atherosclerosis and potent hepatoprotective and free radical scavenging abilities along with its acute and sub-chronic toxicological evaluations are also reported from our laboratory. In keeping with its traditional uses, CG extract was capable of ameliorating experimentally induced hypertension, diabetes and obesity. Its beneficial potential against NASH induced oxidative stress and atherosclerosis can be attributed to its potent free radical scavenging potential. Non-toxic nature of CG leaf extract further provides added merit to its reported pharmacological properties. The present review summarizes the pioneering scientific evidence for the pharmacological effects of CG against related metabolic disorders like hypertension, diabetes and obesity along with anti oxidant potential and beneficial effects against non alcoholic steatohepatitis.

Original languageEnglish (US)
Pages (from-to)1-6
Number of pages6
JournalAsian Pacific Journal of Tropical Medicine
Volume5
Issue number1
DOIs
StatePublished - Jan 2012
Externally publishedYes

Keywords

  • Atherosclerosis
  • Clerodendron glandulosum. Coleb
  • Hypertension
  • Insulin resistance
  • Obesity

ASJC Scopus subject areas

  • Medicine(all)

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