Translational research on Barrett's esophagus

Anushka Baruah, Navtej Buttar, Raghav Chandra, Xiaoxin Chen, Nicholas J. Clemons, Debora Compare, Wael El-Rifai, Jian Gu, Courtney W. Houchen, Shze Yung Koh, Wenbo Li, Gerardo Nardone, Wayne A. Phillips, Anamay Sharma, Ishtpreet Singh, Melissa P. Upton, Kenneth J. Vega, Xifeng Wu

Research output: Contribution to journalArticle

4 Scopus citations

Abstract

The following, from the 12th OESO World Conference: Cancers of the Esophagus, includes commentaries on translational research on Barrett's esophagus that address evidence for genetic instability in esophageal cancer; the role of microsatellite instability; the use of histologic and serum Doublecortin-like kinase 1 expression for progression of Barrett's esophagus to adenocarcinoma; the oxidative stress in Barrett's tumorigenesis; the genomic alterations in esophageal cancer; in vivo modeling in Barrett's esophagus; epigenetic and transcriptional regulation in Barrett's esophagus and esophageal adenocarcinoma; and normal and disordered regeneration in Barrett's esophagus.

Original languageEnglish (US)
Pages (from-to)170-186
Number of pages17
JournalAnnals of the New York Academy of Sciences
Volume1325
Issue number1
DOIs
StatePublished - Sep 1 2014
Externally publishedYes

Keywords

  • Barrett's esophagus
  • DCLK
  • Esophageal adenocarcinoma
  • Microsatellite instability
  • Modeling
  • OESO
  • Oxidative stress

ASJC Scopus subject areas

  • Neuroscience(all)
  • Biochemistry, Genetics and Molecular Biology(all)
  • History and Philosophy of Science

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  • Cite this

    Baruah, A., Buttar, N., Chandra, R., Chen, X., Clemons, N. J., Compare, D., El-Rifai, W., Gu, J., Houchen, C. W., Koh, S. Y., Li, W., Nardone, G., Phillips, W. A., Sharma, A., Singh, I., Upton, M. P., Vega, K. J., & Wu, X. (2014). Translational research on Barrett's esophagus. Annals of the New York Academy of Sciences, 1325(1), 170-186. https://doi.org/10.1111/nyas.12531