Treatment of Laryngeal Carcinoma With Conservative Surgery and Postoperative Radiation Therapy

Helmuth Goepfert, Howard A. Zaren, Richard H. Jesse, Robert Lindberg

Research output: Contribution to journalArticle

16 Citations (Scopus)

Abstract

Thirteen patients with carcinoma of the supraglottic larynx (N = 10), vocal cord (N = 2), and pyriform sinus (N = 1) were treated with conservative surgery followed by radiation therapy. This plan was chosen because clinically or histologically proven lymph node metastases were present and because the primary cancer had one or more of the following factors that were adverse to patient survival: (1) the tumor extended beyond the limits of safe, conservative laryngeal surgery; (2) it infiltrated surrounding soft tissues, ie, preepiglottic space; (3) it was close to the resected margin; and (4) perineural invasion was present. Laryngeal function has been adequate in all but two patients: one has persistent aspiration one year after treatment, and one has a narrow airway after an extended supraglottic laryngectomy that included the anterior third of both cords and a portion of the subglottis at the anterior commissure with adjacent thyroid cartilage. One patient died in the immediate postoperative period, and this case cannot be evaluated. Twelve patients who completed treatment have been followed up for a median of 30 months (1½ through 3½ years), and all have remained free of recurrent disease.

Original languageEnglish (US)
Pages (from-to)576-578
Number of pages3
JournalArchives of Otolaryngology
Volume104
Issue number10
DOIs
StatePublished - Jan 1 1978
Externally publishedYes

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Radiotherapy
Carcinoma
Pyriform Sinus
Thyroid Cartilage
Therapeutics
Laryngectomy
Vocal Cords
Larynx
Postoperative Period
Neoplasms
Lymph Nodes
Neoplasm Metastasis
Survival

ASJC Scopus subject areas

  • Otorhinolaryngology

Cite this

Treatment of Laryngeal Carcinoma With Conservative Surgery and Postoperative Radiation Therapy. / Goepfert, Helmuth; Zaren, Howard A.; Jesse, Richard H.; Lindberg, Robert.

In: Archives of Otolaryngology, Vol. 104, No. 10, 01.01.1978, p. 576-578.

Research output: Contribution to journalArticle

Goepfert, Helmuth ; Zaren, Howard A. ; Jesse, Richard H. ; Lindberg, Robert. / Treatment of Laryngeal Carcinoma With Conservative Surgery and Postoperative Radiation Therapy. In: Archives of Otolaryngology. 1978 ; Vol. 104, No. 10. pp. 576-578.
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