Treatment of Neurogenic Cough with Tramadol: A Pilot Study

Gregory R. Dion, Stephanie E. Teng, Efstratios Achlatis, Yixin Fang, Milan R. Amin

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

This study employs validated cough assessment tools to prospectively determine the impact of tramadol on cough severity and quality of life in subjects with neurogenic cough. The study was a prospective case series with planned data collection at a tertiary care academic medical center laryngology practice. Sixteen consecutive collected subjects with neurogenic cough prospectively completed pre- and posttreatment validated cough assessment tools, the cough severity index (CSI) and Leicester Cough Questionnaire (LCQ). All subjects in the study reported at least some improvement in their cough symptoms. In a Wilcoxon signed rank test that compared paired results, CSI scores improved from 23 to 14 and LCQ scores improved from 74 to 103 (P =.003 and P =.005, respectively). This small preliminary assessment suggests that tramadol warrants additional evaluation as a treatment for neurogenic cough.

Original languageEnglish (US)
Pages (from-to)77-79
Number of pages3
JournalOtolaryngology - Head and Neck Surgery (United States)
Volume157
Issue number1
DOIs
StatePublished - Jul 1 2017

Fingerprint

Tramadol
Cough
Otolaryngology
Tertiary Healthcare
Nonparametric Statistics
Quality of Life

Keywords

  • cough
  • neurogenic cough
  • neurogenic cough treatment
  • neuropathic cough treatment
  • tramadol

ASJC Scopus subject areas

  • Surgery
  • Otorhinolaryngology

Cite this

Treatment of Neurogenic Cough with Tramadol : A Pilot Study. / Dion, Gregory R.; Teng, Stephanie E.; Achlatis, Efstratios; Fang, Yixin; Amin, Milan R.

In: Otolaryngology - Head and Neck Surgery (United States), Vol. 157, No. 1, 01.07.2017, p. 77-79.

Research output: Contribution to journalArticle

Dion, Gregory R. ; Teng, Stephanie E. ; Achlatis, Efstratios ; Fang, Yixin ; Amin, Milan R. / Treatment of Neurogenic Cough with Tramadol : A Pilot Study. In: Otolaryngology - Head and Neck Surgery (United States). 2017 ; Vol. 157, No. 1. pp. 77-79.
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