Tubular cells produce FGF2 via autophagy after acute kidney injury leading to fibroblast activation and renal fibrosis

Medicine & Life Sciences

• Fibroblast Growth Factor 2 100%
• Autophagy 90%
• Acute Kidney Injury 89%
• Fibrosis 69%
• Fibroblasts 69%
• Kidney 50%
• Proto-Oncogene Proteins c-sis 20%
• Actins 18%
• Blood Urea Nitrogen 15%
• Hepatitis A Virus Cellular Receptor 1 14%
• Transforming Growth Factor beta 13%
• cyclophilin B 12%
• fucose-binding lectin 12%
• alpha 1 chain collagen type I 12%
• Galactosidases 10%
• Cyclin-Dependent Kinase Inhibitor p16 10%
• Peptidylprolyl Isomerase 10%
• Enzyme-Linked Immunosorbent Assay 10%
• Macroautophagy 10%
• Glyceraldehyde-3-Phosphate Dehydrogenases 9%
• Phenotype 8%
• Collagen Type IV 8%
• Microtubule-Associated Proteins 8%
• Chloroquine 8%
• Cellular Senescence 7%
• Sirolimus 7%
• Vimentin 7%
• Conditioned Culture Medium 7%
• Neutralizing Antibodies 7%
• Fibronectins 7%
• Reperfusion Injury 6%
• Glomerular Filtration Rate 6%
• Chronic Renal Insufficiency 6%
• Culture Media 6%
• In Situ Hybridization 6%
• Smooth Muscle 6%
• Aorta 6%
• Extracellular Matrix 6%
• Psychological Inhibition 5%
• Creatinine 5%
• Real-Time Polymerase Chain Reaction 5%
• Phosphotransferases 5%
• Communication 5%
• Light 5%
• Immunohistochemistry 5%
• Peptides 4%
• Cytokines 4%
• Biopsy 4%
• Wounds and Injuries 3%
• Serum 3%