### Abstract

OBJECTIVE: Our objective was to compare the ability of two methods of amniotic fluid assessment (two-diameter amniotic fluid pocket versus the amniotic fluid index) to predict oligohydramnios (actual amniotic fluid volume <500 ml) or polyhydramnios (actual amniotic fluid volume >1500 ml). STUDY DESIGN: The amniotic fluid index and the two-diameter amniotic fluid Docket were assessed before amniocentesis and determination of amniotic fluid volume with the dye (aminohippurate sodium)-dilution technique. To assess the detection of either oligohydramnios or polyhydramnios, the areas under the receiver-operator characteristic curves (±SE) were estimated by the point- to-point trapezoidal method of integration. Prediction limits were calculated by regression analysis of amniotic fluid index or two-diameter amniotic fluid pocket versus actual amniotic fluid volume and determination of 95th percentile ranges for amniotic fluid volume. RESULTS: We studied 144 patients with a mean (±SD) gestational age of 31.7 ± 5.5 weeks; mean (±SD) amniotic fluid index and two-diameter amniotic fluid pocket were 12.6 ± 6.1 cm and 21.2 ± 18.4 cm^{2}, respectively. Mean (±SD) actual amniotic fluid volume was 722 ± 735 ml (range 101 to 4318 ml). The areas under the four receiver- operator characteristic curves were not significantly different from the nondiagnostic line (p < 0.05). Regression slopes (r values) for amniotic fluid index and two-diameter amniotic fluid pocket versus actual amniotic fluid volume were 0.34 and 0.23, respectively. Calculation of the prediction limit for 95% confidence that oligohydramnios is absent requires that the amniotic fluid index be 30 cm and the two-dimension amniotic fluid Docket be 90 cm^{2}, both thresholds of which are currently considered to represent clinical polyhydramnios. CONCLUSIONS: Both amniotic fluid index and two- dimension amniotic fluid pocket appear to be inaccurate predictors of actual oligohydramnios or polyhydramnios when compared with dye-dilution calculations of actual amniotic fluid volume.

Original language | English (US) |
---|---|

Pages (from-to) | 291-297 |

Number of pages | 7 |

Journal | American Journal of Obstetrics and Gynecology |

Volume | 177 |

Issue number | 2 |

DOIs | |

State | Published - Jan 1 1997 |

### Fingerprint

### Keywords

- Amniotic fluid index
- Amniotic fluid volume

### ASJC Scopus subject areas

- Obstetrics and Gynecology

### Cite this

*American Journal of Obstetrics and Gynecology*,

*177*(2), 291-297. https://doi.org/10.1016/S0002-9378(97)70189-3

**Ultrasonographic assessment of amniotic fluid does not reflect actual amniotic fluid volume.** / Chauhan, S. P.; Magann, E. F.; Morrison, J. C.; Whirworth, N. S.; Hendrix, N. W.; Devoe, Lawrence D; Wade, R. V.

Research output: Contribution to journal › Article

*American Journal of Obstetrics and Gynecology*, vol. 177, no. 2, pp. 291-297. https://doi.org/10.1016/S0002-9378(97)70189-3

}

TY - JOUR

T1 - Ultrasonographic assessment of amniotic fluid does not reflect actual amniotic fluid volume

AU - Chauhan, S. P.

AU - Magann, E. F.

AU - Morrison, J. C.

AU - Whirworth, N. S.

AU - Hendrix, N. W.

AU - Devoe, Lawrence D

AU - Wade, R. V.

PY - 1997/1/1

Y1 - 1997/1/1

N2 - OBJECTIVE: Our objective was to compare the ability of two methods of amniotic fluid assessment (two-diameter amniotic fluid pocket versus the amniotic fluid index) to predict oligohydramnios (actual amniotic fluid volume <500 ml) or polyhydramnios (actual amniotic fluid volume >1500 ml). STUDY DESIGN: The amniotic fluid index and the two-diameter amniotic fluid Docket were assessed before amniocentesis and determination of amniotic fluid volume with the dye (aminohippurate sodium)-dilution technique. To assess the detection of either oligohydramnios or polyhydramnios, the areas under the receiver-operator characteristic curves (±SE) were estimated by the point- to-point trapezoidal method of integration. Prediction limits were calculated by regression analysis of amniotic fluid index or two-diameter amniotic fluid pocket versus actual amniotic fluid volume and determination of 95th percentile ranges for amniotic fluid volume. RESULTS: We studied 144 patients with a mean (±SD) gestational age of 31.7 ± 5.5 weeks; mean (±SD) amniotic fluid index and two-diameter amniotic fluid pocket were 12.6 ± 6.1 cm and 21.2 ± 18.4 cm2, respectively. Mean (±SD) actual amniotic fluid volume was 722 ± 735 ml (range 101 to 4318 ml). The areas under the four receiver- operator characteristic curves were not significantly different from the nondiagnostic line (p < 0.05). Regression slopes (r values) for amniotic fluid index and two-diameter amniotic fluid pocket versus actual amniotic fluid volume were 0.34 and 0.23, respectively. Calculation of the prediction limit for 95% confidence that oligohydramnios is absent requires that the amniotic fluid index be 30 cm and the two-dimension amniotic fluid Docket be 90 cm2, both thresholds of which are currently considered to represent clinical polyhydramnios. CONCLUSIONS: Both amniotic fluid index and two- dimension amniotic fluid pocket appear to be inaccurate predictors of actual oligohydramnios or polyhydramnios when compared with dye-dilution calculations of actual amniotic fluid volume.

AB - OBJECTIVE: Our objective was to compare the ability of two methods of amniotic fluid assessment (two-diameter amniotic fluid pocket versus the amniotic fluid index) to predict oligohydramnios (actual amniotic fluid volume <500 ml) or polyhydramnios (actual amniotic fluid volume >1500 ml). STUDY DESIGN: The amniotic fluid index and the two-diameter amniotic fluid Docket were assessed before amniocentesis and determination of amniotic fluid volume with the dye (aminohippurate sodium)-dilution technique. To assess the detection of either oligohydramnios or polyhydramnios, the areas under the receiver-operator characteristic curves (±SE) were estimated by the point- to-point trapezoidal method of integration. Prediction limits were calculated by regression analysis of amniotic fluid index or two-diameter amniotic fluid pocket versus actual amniotic fluid volume and determination of 95th percentile ranges for amniotic fluid volume. RESULTS: We studied 144 patients with a mean (±SD) gestational age of 31.7 ± 5.5 weeks; mean (±SD) amniotic fluid index and two-diameter amniotic fluid pocket were 12.6 ± 6.1 cm and 21.2 ± 18.4 cm2, respectively. Mean (±SD) actual amniotic fluid volume was 722 ± 735 ml (range 101 to 4318 ml). The areas under the four receiver- operator characteristic curves were not significantly different from the nondiagnostic line (p < 0.05). Regression slopes (r values) for amniotic fluid index and two-diameter amniotic fluid pocket versus actual amniotic fluid volume were 0.34 and 0.23, respectively. Calculation of the prediction limit for 95% confidence that oligohydramnios is absent requires that the amniotic fluid index be 30 cm and the two-dimension amniotic fluid Docket be 90 cm2, both thresholds of which are currently considered to represent clinical polyhydramnios. CONCLUSIONS: Both amniotic fluid index and two- dimension amniotic fluid pocket appear to be inaccurate predictors of actual oligohydramnios or polyhydramnios when compared with dye-dilution calculations of actual amniotic fluid volume.

KW - Amniotic fluid index

KW - Amniotic fluid volume

UR - http://www.scopus.com/inward/record.url?scp=0030983878&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0030983878&partnerID=8YFLogxK

U2 - 10.1016/S0002-9378(97)70189-3

DO - 10.1016/S0002-9378(97)70189-3

M3 - Article

VL - 177

SP - 291

EP - 297

JO - American Journal of Obstetrics and Gynecology

JF - American Journal of Obstetrics and Gynecology

SN - 0002-9378

IS - 2

ER -