Ultrasound assessment of flow-mediated dilation

Ryan A. Harris, Steven K. Nishiyama, D. Walter Wray, Russell S. Richardson

Research output: Contribution to journalReview article

308 Scopus citations


Developed in 1992, the flow-mediated dilation test is now the most commonly used noninvasive assessment of vascular endothelial function in humans. Since its inception, scientists have refined their understanding of the physiology, analysis, and interpretation of this measurement. Recently, a significant growth of knowledge has added to our understanding and implementation of this clinically relevant research methodology. Therefore, this tutorial provides timely insight into recent advances and practical information related to the ultrasonic assessment of vascular endothelial function in humans.

Original languageEnglish (US)
Pages (from-to)1075-1085
Number of pages11
Issue number5
Publication statusPublished - May 1 2010



  • Endothelial function
  • FMD
  • Reactive hyperemia
  • Shear stress

ASJC Scopus subject areas

  • Internal Medicine

Cite this

Harris, R. A., Nishiyama, S. K., Wray, D. W., & Richardson, R. S. (2010). Ultrasound assessment of flow-mediated dilation. Hypertension, 55(5), 1075-1085. https://doi.org/10.1161/HYPERTENSIONAHA.110.150821