Abstract
Background: Cerebral cavernous malformations (CCM) are an uncommon delayed late complication of brain radiotherapy in adults. Aim: Describe an adult treated for a malignant glioma with chemotherapy and radiotherapy who subsequently presented with multiple CCM. Methods: Case report and literature review of CCM. Results: Multiple CCM were discovered in an adult following presentation with a symptomatic intracranial hemorrhage. Conclusion: The occurrence of CCM is an unusual delayed late radiation side effect following treatment of CNS tumors. Gradient echo MRI should be considered as a standard sequence in patients with previously treated brain tumors.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 673-676 |
| Number of pages | 4 |
| Journal | Therapy |
| Volume | 4 |
| Issue number | 5 |
| DOIs | |
| State | Published - Sep 1 2007 |
Fingerprint
Keywords
- Cerebral cavernous malformation
- Complication of brain radiotherapy
ASJC Scopus subject areas
- Pharmacology (medical)
Cite this
Underappreciated delayed late complication of adult brain irradiation : Development of cerebral cavernous malformations. / Chowdhary, Sajeel; Sloan, Andrew; Rojiani, Amyn M.; Chamberlain, Marc.
In: Therapy, Vol. 4, No. 5, 01.09.2007, p. 673-676.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Underappreciated delayed late complication of adult brain irradiation
T2 - Development of cerebral cavernous malformations
AU - Chowdhary, Sajeel
AU - Sloan, Andrew
AU - Rojiani, Amyn M.
AU - Chamberlain, Marc
PY - 2007/9/1
Y1 - 2007/9/1
N2 - Background: Cerebral cavernous malformations (CCM) are an uncommon delayed late complication of brain radiotherapy in adults. Aim: Describe an adult treated for a malignant glioma with chemotherapy and radiotherapy who subsequently presented with multiple CCM. Methods: Case report and literature review of CCM. Results: Multiple CCM were discovered in an adult following presentation with a symptomatic intracranial hemorrhage. Conclusion: The occurrence of CCM is an unusual delayed late radiation side effect following treatment of CNS tumors. Gradient echo MRI should be considered as a standard sequence in patients with previously treated brain tumors.
AB - Background: Cerebral cavernous malformations (CCM) are an uncommon delayed late complication of brain radiotherapy in adults. Aim: Describe an adult treated for a malignant glioma with chemotherapy and radiotherapy who subsequently presented with multiple CCM. Methods: Case report and literature review of CCM. Results: Multiple CCM were discovered in an adult following presentation with a symptomatic intracranial hemorrhage. Conclusion: The occurrence of CCM is an unusual delayed late radiation side effect following treatment of CNS tumors. Gradient echo MRI should be considered as a standard sequence in patients with previously treated brain tumors.
KW - Cerebral cavernous malformation
KW - Complication of brain radiotherapy
UR - http://www.scopus.com/inward/record.url?scp=35348843526&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=35348843526&partnerID=8YFLogxK
U2 - 10.2217/14750708.4.5.673
DO - 10.2217/14750708.4.5.673
M3 - Article
AN - SCOPUS:35348843526
VL - 4
SP - 673
EP - 676
JO - Therapy
JF - Therapy
SN - 2044-9038
IS - 5
ER -