TY - JOUR
T1 - Underappreciated delayed late complication of adult brain irradiation
T2 - Development of cerebral cavernous malformations
AU - Chowdhary, Sajeel
AU - Sloan, Andrew
AU - Rojiani, Amyn M.
AU - Chamberlain, Marc
PY - 2007/9
Y1 - 2007/9
N2 - Background: Cerebral cavernous malformations (CCM) are an uncommon delayed late complication of brain radiotherapy in adults. Aim: Describe an adult treated for a malignant glioma with chemotherapy and radiotherapy who subsequently presented with multiple CCM. Methods: Case report and literature review of CCM. Results: Multiple CCM were discovered in an adult following presentation with a symptomatic intracranial hemorrhage. Conclusion: The occurrence of CCM is an unusual delayed late radiation side effect following treatment of CNS tumors. Gradient echo MRI should be considered as a standard sequence in patients with previously treated brain tumors.
AB - Background: Cerebral cavernous malformations (CCM) are an uncommon delayed late complication of brain radiotherapy in adults. Aim: Describe an adult treated for a malignant glioma with chemotherapy and radiotherapy who subsequently presented with multiple CCM. Methods: Case report and literature review of CCM. Results: Multiple CCM were discovered in an adult following presentation with a symptomatic intracranial hemorrhage. Conclusion: The occurrence of CCM is an unusual delayed late radiation side effect following treatment of CNS tumors. Gradient echo MRI should be considered as a standard sequence in patients with previously treated brain tumors.
KW - Cerebral cavernous malformation
KW - Complication of brain radiotherapy
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U2 - 10.2217/14750708.4.5.673
DO - 10.2217/14750708.4.5.673
M3 - Article
AN - SCOPUS:35348843526
VL - 4
SP - 673
EP - 676
JO - Therapy
JF - Therapy
SN - 1475-0708
IS - 5
ER -