Underappreciated delayed late complication of adult brain irradiation: Development of cerebral cavernous malformations

Sajeel Chowdhary, Andrew Sloan, Amyn M. Rojiani, Marc Chamberlain

Research output: Contribution to journalArticle

Abstract

Background: Cerebral cavernous malformations (CCM) are an uncommon delayed late complication of brain radiotherapy in adults. Aim: Describe an adult treated for a malignant glioma with chemotherapy and radiotherapy who subsequently presented with multiple CCM. Methods: Case report and literature review of CCM. Results: Multiple CCM were discovered in an adult following presentation with a symptomatic intracranial hemorrhage. Conclusion: The occurrence of CCM is an unusual delayed late radiation side effect following treatment of CNS tumors. Gradient echo MRI should be considered as a standard sequence in patients with previously treated brain tumors.

Original languageEnglish (US)
Pages (from-to)673-676
Number of pages4
JournalTherapy
Volume4
Issue number5
DOIs
StatePublished - Sep 1 2007

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Central Nervous System Cavernous Hemangioma
Brain
Radiotherapy
Intracranial Hemorrhages
Radiation Effects
Brain Neoplasms
Glioma
Drug Therapy
Neoplasms

Keywords

  • Cerebral cavernous malformation
  • Complication of brain radiotherapy

ASJC Scopus subject areas

  • Pharmacology (medical)

Cite this

Underappreciated delayed late complication of adult brain irradiation : Development of cerebral cavernous malformations. / Chowdhary, Sajeel; Sloan, Andrew; Rojiani, Amyn M.; Chamberlain, Marc.

In: Therapy, Vol. 4, No. 5, 01.09.2007, p. 673-676.

Research output: Contribution to journalArticle

Chowdhary, Sajeel ; Sloan, Andrew ; Rojiani, Amyn M. ; Chamberlain, Marc. / Underappreciated delayed late complication of adult brain irradiation : Development of cerebral cavernous malformations. In: Therapy. 2007 ; Vol. 4, No. 5. pp. 673-676.
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