Unilateral basal cell carcinomas

An unusual entity treated with photodynamic therapy

Joshua E. Lane, Jennifer H. Allen, Tanda N. Lane, Jack L. Lesher

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

Background: Unilateral localized basal cell carcinomas are an uncommon finding that presents both a diagnostic and therapeutic challenge. Exclusion of unilateral nevoid basal cell carcinoma syndrome is indicated. There are few reports in the literature regarding this entity and even less regarding therapeutic strategies. Objective: We present a patient with unilateral localized basal cell carcinomas who was successfully treated with photodynamic therapy. Methods: Photodynamic therapy was started using Levulan® Kerastick® as previously described. The topical solution was applied to the patient's back and illuminated the following day via the BLU-U Blue Light Illuminator. Results: The patient tolerated the procedure well and without complications. The patient had an excellent therapeutic response with no clinically apparent basal cell carcinomas for 18 months. Conclusions: We report a patient with unilateral basal cell carcinomas successfully treated with photodynamic therapy. This uncommon entity represents a diagnostic challenge in its inherent absence of the classic clinical and radiographic findings of nevoid basal cell carcinoma syndrome. Like nevoid basal cell carcinoma syndrome, unilateral basal cell carcinomas poses a therapeutic challenge with the sheer number of cutaneous tumors. The use of photodynamic therapy carries a proven therapeutic efficacy, a low rate of adverse events and excellent cosmesis.

Original languageEnglish (US)
Pages (from-to)336-340
Number of pages5
JournalJournal of Cutaneous Medicine and Surgery
Volume9
Issue number6
DOIs
StatePublished - Dec 1 2005

Fingerprint

Basal Cell Carcinoma
Photochemotherapy
Basal Cell Nevus Syndrome
Therapeutics
Aminolevulinic Acid
Light
Skin
Neoplasms

ASJC Scopus subject areas

  • Surgery
  • Dermatology

Cite this

Unilateral basal cell carcinomas : An unusual entity treated with photodynamic therapy. / Lane, Joshua E.; Allen, Jennifer H.; Lane, Tanda N.; Lesher, Jack L.

In: Journal of Cutaneous Medicine and Surgery, Vol. 9, No. 6, 01.12.2005, p. 336-340.

Research output: Contribution to journalArticle

Lane, Joshua E. ; Allen, Jennifer H. ; Lane, Tanda N. ; Lesher, Jack L. / Unilateral basal cell carcinomas : An unusual entity treated with photodynamic therapy. In: Journal of Cutaneous Medicine and Surgery. 2005 ; Vol. 9, No. 6. pp. 336-340.
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