Unusual Contiguous Soft Tissue Spread of Advanced Malignant Mesothelioma Detected by FDG PET/CT

Yuyang Zhang, Jamie Edwards, Hadyn T Williams, Zhonglin Hao, Samir N. Khleif, Darko Pucar

Research output: Contribution to journalArticle


Malignant pleural mesothelioma (MPM) is a tumor of mesodermal origin that arises from the serosa of the pleura, peritoneum, pericardium or tunica vaginalis. MPM is well known to have a poor prognosis with a median survival time of 12 months. Accurate diagnosis, staging and restaging of MPM are crucial with [18F] flurodeoxy-D-glucose positron emission tomography (FDG PET/CT) playing an increasingly important role. Here we report a case of MPM with unusual contiguous soft tissue spread of the tumor along the dermal and fascial planes characterized by PET/CT. Given that the loco-regional tumor in the thorax was under control on PET/CT, the death of the patient was most likely associated with physiologic or metabolic causes associated with an extra-thoracic tumor.

Original languageEnglish (US)
Pages (from-to)178-181
Number of pages4
JournalNuclear Medicine and Molecular Imaging
Issue number2
StatePublished - Jun 1 2017



  • Adjuvant chemotherapy
  • Malignant mesothelioma
  • Metastases

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

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