Unusual presentation of extranodal diffuse large B-cell lymphoma in the head and neck

Description of a case with emphasis on radiographic features and review of the literature

Allison Buchanan, Sajitha Kalathingal, Jeffrey Capes, Zoya Kurago

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

A very unusual radiographic presentation of non-Hodgkin lymphoma (NHL) involving the maxilla is described. The patient was initially managed with antibiotics prescribed to treat what was thought to represent an odontogenic infection. After unsuccessful antibiotic therapy, the patient was referred to an oral surgery clinic where CBCT was performed. CBCT revealed an atypical generalized sclerosis of the affected bone rather than the usual lytic radiographic pattern associated with NHL. Destruction of the sinus floor with infiltration of the sinus was also present. This rare radio-opaque radiographic presentation is described in detail together with the clinical presentation and histopathological findings. The important radiographic features suggesting malignancy that were present in this atypical case of NHL are discussed. A differential diagnosis highlighting the differences between NHL, osteomyelitis and osteosarcoma is also provided.

Original languageEnglish (US)
Article number20140288
JournalDentomaxillofacial Radiology
Volume44
Issue number3
DOIs
StatePublished - Nov 25 2014

Fingerprint

Lymphoma, Large B-Cell, Diffuse
Non-Hodgkin's Lymphoma
Neck
Head
Anti-Bacterial Agents
Oral Surgery
Maxilla
Sclerosis
Osteosarcoma
Osteomyelitis
Differential Diagnosis
Bone and Bones
Infection
Neoplasms
Therapeutics

Keywords

  • Cone beam CT
  • Extranodal lymphoma
  • Head and neck
  • Sclerotic

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Otorhinolaryngology
  • Dentistry(all)

Cite this

Unusual presentation of extranodal diffuse large B-cell lymphoma in the head and neck : Description of a case with emphasis on radiographic features and review of the literature. / Buchanan, Allison; Kalathingal, Sajitha; Capes, Jeffrey; Kurago, Zoya.

In: Dentomaxillofacial Radiology, Vol. 44, No. 3, 20140288, 25.11.2014.

Research output: Contribution to journalArticle

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