Vagus nerve stimulation and drug reduction

William O. Tatum IV, K. D. Johnson, S. Goff, J. A. Ferreira, S. R. Benbadis, Fernando Vale Diaz

Research output: Contribution to journalArticle

52 Citations (Scopus)

Abstract

The authors prospectively assessed drug reduction and patient satisfaction in 21 patients using vagus nerve stimulation (VNS) for refractory epilepsy and compared results to a case-matched control group with a mean follow-up of 13.2 months. Significant antiepileptic drug (AED) reduction occurred in 9/21 (42.9)% of VNS patients averaging 0.43 AED/patient, with dose reduction in four patients (19.0%). For 12/21 (57.1%) patients not reducing AED, dose reduction occurred in 6/21 (28.6%). Drug and dose reduction of AED is possible in patients using VNS for refractory epilepsy without loss of seizure control and with improved patient satisfaction.

Original languageEnglish (US)
Pages (from-to)561-563
Number of pages3
JournalNeurology
Volume56
Issue number4
DOIs
StatePublished - Feb 27 2001
Externally publishedYes

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Vagus Nerve Stimulation
Anticonvulsants
Pharmaceutical Preparations
Patient Satisfaction
Epilepsy
Seizures
Research Design
Control Groups

ASJC Scopus subject areas

  • Clinical Neurology

Cite this

Tatum IV, W. O., Johnson, K. D., Goff, S., Ferreira, J. A., Benbadis, S. R., & Vale Diaz, F. (2001). Vagus nerve stimulation and drug reduction. Neurology, 56(4), 561-563. https://doi.org/10.1212/WNL.56.4.561

Vagus nerve stimulation and drug reduction. / Tatum IV, William O.; Johnson, K. D.; Goff, S.; Ferreira, J. A.; Benbadis, S. R.; Vale Diaz, Fernando.

In: Neurology, Vol. 56, No. 4, 27.02.2001, p. 561-563.

Research output: Contribution to journalArticle

Tatum IV, WO, Johnson, KD, Goff, S, Ferreira, JA, Benbadis, SR & Vale Diaz, F 2001, 'Vagus nerve stimulation and drug reduction', Neurology, vol. 56, no. 4, pp. 561-563. https://doi.org/10.1212/WNL.56.4.561
Tatum IV WO, Johnson KD, Goff S, Ferreira JA, Benbadis SR, Vale Diaz F. Vagus nerve stimulation and drug reduction. Neurology. 2001 Feb 27;56(4):561-563. https://doi.org/10.1212/WNL.56.4.561
Tatum IV, William O. ; Johnson, K. D. ; Goff, S. ; Ferreira, J. A. ; Benbadis, S. R. ; Vale Diaz, Fernando. / Vagus nerve stimulation and drug reduction. In: Neurology. 2001 ; Vol. 56, No. 4. pp. 561-563.
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