Vagus nerve stimulation and drug reduction

William O. Tatum IV, K. D. Johnson, S. Goff, J. A. Ferreira, S. R. Benbadis, F. L. Vale

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Abstract

The authors prospectively assessed drug reduction and patient satisfaction in 21 patients using vagus nerve stimulation (VNS) for refractory epilepsy and compared results to a case-matched control group with a mean follow-up of 13.2 months. Significant antiepileptic drug (AED) reduction occurred in 9/21 (42.9)% of VNS patients averaging 0.43 AED/patient, with dose reduction in four patients (19.0%). For 12/21 (57.1%) patients not reducing AED, dose reduction occurred in 6/21 (28.6%). Drug and dose reduction of AED is possible in patients using VNS for refractory epilepsy without loss of seizure control and with improved patient satisfaction.

Original languageEnglish (US)
Pages (from-to)561-563
Number of pages3
JournalNeurology
Volume56
Issue number4
DOIs
Publication statusPublished - Feb 27 2001
Externally publishedYes

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ASJC Scopus subject areas

  • Clinical Neurology

Cite this

Tatum IV, W. O., Johnson, K. D., Goff, S., Ferreira, J. A., Benbadis, S. R., & Vale, F. L. (2001). Vagus nerve stimulation and drug reduction. Neurology, 56(4), 561-563. https://doi.org/10.1212/WNL.56.4.561