Validation of a Mini-Mental State Examination (MMSE) for the Persian population: A pilot study

Noureddin Nakhostin Ansari, Soofia Naghdi, Scott Hasson, Leala Valizadeh, Shohreh Jalaie

Research output: Contribution to journalArticle

62 Scopus citations

Abstract

The objective of the study was to develop and validate a translated and culturally adapted Mini-Mental State Examination (MMSE) for the Persian-speaking population. The MMSE was translated into Persian. Two groups of neurologically intact subjects (n=100) and subjects with Alzheimer's disease (n=13) were studied. The difference between groups on the mean total scores of the Persian MMSE was statistically significant (control=28.62±2.09; subjects with Alzheimer's disease=11.77±5.66; p≤.001). The cutoff score of 23 was the best cutoff score for our subjects with a sensitivity and specificity of 98% and 100%, respectively. There was a significant correlation between the Persian MMSE score and the level of education (r=.46) and with age (r=-.77). There was no significant correlation between the Persian MMSE and gender. The Persian MMSE was found to be valid for discrimination of cognitive impairment in the Persian-speaking community.

Original languageEnglish (US)
Pages (from-to)190-195
Number of pages6
JournalApplied Neuropsychology
Volume17
Issue number3
DOIs
StatePublished - Jul 1 2010

Keywords

  • Alzheimer's disease
  • Mini-Mental State Examination
  • Persian language

ASJC Scopus subject areas

  • Neuropsychology and Physiological Psychology
  • Developmental and Educational Psychology
  • Arts and Humanities (miscellaneous)

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