The objective of the study was to develop and validate a translated and culturally adapted Mini-Mental State Examination (MMSE) for the Persian-speaking population. The MMSE was translated into Persian. Two groups of neurologically intact subjects (n=100) and subjects with Alzheimer's disease (n=13) were studied. The difference between groups on the mean total scores of the Persian MMSE was statistically significant (control=28.62±2.09; subjects with Alzheimer's disease=11.77±5.66; p≤.001). The cutoff score of 23 was the best cutoff score for our subjects with a sensitivity and specificity of 98% and 100%, respectively. There was a significant correlation between the Persian MMSE score and the level of education (r=.46) and with age (r=-.77). There was no significant correlation between the Persian MMSE and gender. The Persian MMSE was found to be valid for discrimination of cognitive impairment in the Persian-speaking community.
- Alzheimer's disease
- Mini-Mental State Examination
- Persian language
ASJC Scopus subject areas
- Neuropsychology and Physiological Psychology
- Developmental and Educational Psychology
- Arts and Humanities (miscellaneous)